Chemotherapy-enhanced endoscopic submucosal En Bloc dissection vs. conventional TURBT for NMIBC: a comparative study.

Purpose: To evaluate the efficacy of integrating en bloc resection, endoscopic submucosal dissection (ESD), and submucosal injection of chemotherapeutic agents with TURBT (cESD-TURBT).

Methods: This retrospective observational study was conducted on patients diagnosed with stage cTa-T1 bladder cancer who received TURBT between December 2020 and July 2023 at Liaoning Cancer Hospital. The participants were grouped on the basis of the type of treatment they received: cESD-TURBT (n = 118) or conventional TURBT (cTURBT, n = 105).

Whole-genome resequencing reveals collagen-related genes in Kele pigs.

Objective: To verify the accuracy of collagen-specific SNP mutation loci of Kele pigs selected by whole genome resequencing, and to excavate collagen-related genes of Kele pigs, so as to lay a foundation for further molecular selection.

Methods: Based on whole genome resequencing, candidate genes related to collagen trait of Kele pig were screened for gene annotation. Through KEGG and GO enrichment analysis of differential genes, we selected four genes that may affect collagen trait of collagen pig, namely COL9A1, COL6A5, COL4A3 and COL4A4.

Ternary Passivation for Enhanced Carrier Transport and Recombination Suppression in Highly Efficient Sn-Based Perovskite Solar Cells.

The exploration of nontoxic Sn-based perovskites as a viable alternative to their toxic Pb-based counterparts has garnered increased attention. However, the power conversion efficiency of Sn-based perovskite solar cells lags significantly behind their Pb-based counterparts. This study presents a ternary passivation strategy aimed at enhancing device performance, employing [6,6]-phenyl-C61-butyric-acid-methyl-ester (PCBM), poly(3-hexylthiophene) (P3HT), and indene C60 bisadduct (ICBA).

Stronger Coupling of Quantum Dots in Hole Transport Layer Through Intermediate Ligand Exchange to Enhance the Efficiency of PbS Quantum Dot Solar Cells.

Nowadays, the extensively used lead sulfide (PbS) quantum dot (QD) hole transport layer (HTL) relies on layer-by-layer method to replace long chain oleic acid (OA) ligands with short 1,2-ethanedithiol (EDT) ligands for preparation. However, the inevitable significant volume shrinkage caused by this traditional method will result in undesired cracks and disordered QD arrangement in the film, along with adverse increased defect density and inhomogeneous energy landscape. To solve the problem, a novel method for EDT passivated PbS QD (PbS-EDT) HTL preparation using small-sized benzoic acid (BA) as intermediate ligands is proposed in this work.

Ferrocene Derivatives for Improving the Efficiency and Stability of MA-Free Perovskite Solar Cells from the Perspective of Inhibiting Ion Migration and Releasing Film Stress.

Further improvement of the performance and stability of inverted perovskite solar cells (PSCs) is necessary for commercialization. Here, ferrocene derivative dibenzoylferrocene (DBzFe) is used as an additive to enhance the performance and stability of MA- and Br- free PSCs. The results show that the introduction of DBzFe not only passivates the defects in the film but also inhibits the ion migration in the film.

Efficiency Enhancement of Wide Bandgap Lead Perovskite Solar Cells with PTAA Surface-Passivated with Monomolecular Layer from the Viewpoint of PTAA Band Bending.

This report is on the efficiency enhancement of wide bandgap lead halide perovskite solar cells (WBG Pb-PVK PSCs) consisting of FACsPbIBr as the light-harvesting layer. WGB Pb-PVK PSCs have attracted attention as the top layer of all perovskite-tandem solar cells. Poly[bis(4-phenyl) (2,4,6-trimethylphenyl) amine] (PTAA), a conductive polymer, is always used as the hole transporting layer (HTL) for Pb-PVK PSCs.

Ssc-mir-221-3p regulates melanin production in Xiang pigs melanocytes by targeting the TYRP1 gene.

Background: MicroRNAs (miRNAs) are small endogenous non-coding RNAs that regulate gene expression by down-regulating it. Several studies have suggested that miRNAs plays a crucial role in mammalian skin color production. The TYRP1 gene, a member of the tyrosine family, is an important candidate gene that affects melanogenesis.

14.31 % Power Conversion Efficiency of Sn-Based Perovskite Solar Cells via Efficient Reduction of Sn.

The photoelectric properties of nontoxic Sn-based perovskite make it a promising alternative to toxic Pb-based perovskite. It has superior photovoltaic performance in comparison to other Pb-free counterparts. The facile oxidation of Sn to Sn presents a notable obstacle in the advancement of perovskite solar cells that utilize Sn, as it adversely affects their stability and performance.

Crystal Orientation Modulation and Defect Passivation for Efficient and Stable Methylammonium-Free Dion-Jacobson Quasi-2D Perovskite Solar Cells.

Dion-Jacobson (DJ) quasi-2D perovskite solar cells (PSCs) have received increasing attention due to their greater potentials in realizing efficient and stable quasi-2D PSCs relative to their Ruddlesden-Popper counterpart. The substitution of methylammonium (MA) with formamidinium is expected to be able to further increase the stability and power conversion efficiency (PCE) of DJ quasi-2D PSCs. Herein, we report a multifunctional additive strategy for preparing high-quality MA-free DJ quasi-2D perovskite films, where 1,1'-carbonyldi(1,2,4-triazole) (CDTA) molecules are incorporated into the perovskite precursor solution.

Detecting urine metabolites of bladder cancer by surface-enhanced Raman spectroscopy.

Aim: Metabolites present in urine reflect the current phenotype of the cancer state. Surface-enhanced Raman spectroscopy (SERS) can be used in urine supernatant or sediment to largely reflect the metabolic status of the body.

Materials & Methods: SERS was performed to detect bladder cancer (BCa) and predict tumour grade from urine supernatant, which contains various system metabolites, as well as from urine sediment, which contains exfoliated tumour cells.

[Effects of light quality on carbon-nitrogen metabolism, growth, and quality of Chinese chives].

We examined the effect of white + red (WR), white + blue (WB), white + green (WG), white + purple (WP) on the carbon-nitrogen metabolism, growth and quality of Chinese chives, with ‘Pingjiu 2’ as the material and white light (W) as the control. The results showed that photosynthetic rate (P) in WR treatment was significantly higher than that in the control (CK) and that there was no difference among WB, WG, WP and CK. The activity of RuBPCase in all the four treatments was higher than that in CK.

Wettability control of conjugated polymer films by electric-field polarization technique.

Polymer film materials with smart wetting surfaces can be widely used in aerospace, petrochemicals, shipbuilding, automotives, energy saving, environmental protection and other fields. Here, the wettability of conjugated polymer poly(3-hexylthiophene) (P3HT) films was accurately controlled by an electric field polarization technique, and transition of the films from being hydrophobic to hydrophilic was successfully achieved. The water contact angle of the P3HT films could be changed from 105.

[Response and adaptation of photosynthesis of cucumber seedlings to high temperature stress].

Cucumber seedlings (Cucumis sativus Jinyou 35) were used to study the effects of high temperature (HT: 42 ℃/32 ℃) and sub-high temperature (SHT: 35 ℃/25 ℃) on its photosynthesis and growth. The results showed that the growth of cucumber seedlings was dramatically inhibited by the high and sub-high temperature stresses. The photosynthetic rate (P) was gradually reduced, while intercellular CO concentration (C) was increased as heat stress lasted.

[Effect of water-nitrogen coupling on photosynthesis and ultrastructure of cucumber leaves under CO enrichment].

Using split plot and then-split plot design, effects of water-nitrogen coupling on photosynthesis and ultrastructure of cucumber (Cucumis sativus) (Jinyou No.35) under CO enrichment were investigated. The main plot had two CO concentrations: ambient CO concentration (400 μmol·mol, A) and doubled CO concentration (800±20 μmol·mol, E).

Effect of wound fluid on chemotherapy sensitivity of T24 bladder cancer cells with different enhancer of zeste homolog 2 status.

The present study investigated the effect of zeste homolog 2 (EZH2) and wound fluid (WF) on chemotherapy sensitivities of T24 bladder cancer cells by using a collagen gel droplet embedded culture-drug sensitivity test (CD-DST). T24 bladder cancer cells with different EZH2 expression levels were co-cultured with postoperative WF from patients with bladder cancer. The CD-DST was performed to detect the sensitivity of tumor cells to gemcitabine and cis-diamminedichloridoplatinum (II) (cisplatin, DDP).

[Effect of grafting on rhizosphere soil environment and its relationship with disease resistance and yield of pepper.].

We investigated the effect of grafting on the root rhizosphere soil microorganisms, physical properties, nutrient content, soil-borne disease and yield of pepper, using 'Weishi' (WS) and 'Buyeding' (BYD) as rootstocks, the cultivar pepper 'Xinfeng 2' (XF) as scion, and the own-root (XF/XF) pepper as the control. The results indicated that XF/WS and XF/BYD significantly increased the populations of fungi and actinomycetes and the percentage of actinomycetes. 60 days after transplanting, the activities of catalase (CAT) and peroxidase (POD) were much higher in root rhizosphere soil of grafted pepper.

[Influence of over expression of CsRCA on photosynthesis of cucumber seedlings under high temperature stress.].

In the present work, transgenic cucumber seedlings over expressing CsRCA and wild-type cucumber seedlings '08-1'at three-leaf stage exposed to high temperature (40 ℃, PFD 600 μmol· m · s) were used to study the regulatory mechanism of photosynthesis by CsRCA. The results showed that the mRNA abundance of rbcL and rbcS as well as the activities of ribulose bisphosphate carboxylic enzyme (Rubisco) and Rubisco activase (RCA) were significantly higher in CsRCA over-expressing cucumber seedlings than in wild type (WT). Following 2-h exposure to high temperature, a notable decrease was observed in photosynthetic rate (P), photochemical perfor-mance index based on the absorption of light energy (PI), activities of Rubisco and RCA as well as the relative expression of rbcL, rbcS and CsRCA in both wild-type cucumber seedlings and transgenic cucumber seedlings.