Integrating Embodied Social Presence Theory and Process Virtualization Theory to assess business process virtualizability: The mediating role of embodied co-presence.

In the digital era, the integration of technology within business processes is pivotal for organizational efficiency. This study investigates the impact of IT characteristics-specifically IT representation, IT reach, and monitoring capability-on the virtualizability of business processes, utilizing the frameworks of Embodied Social Presence Theory (ESPT) and Process Virtualization Theory (PVT). Our objective is to explore how these IT characteristics, through the mediation of embodied co-presence, enhance business process virtualizability in the context of collaborative tools.

Computational construction of TME-related lncRNAs signature for predicting prognosis and immunotherapy response in clear cell renal cell carcinoma.

Background: The tumor microenvironment (TME) is closely related to clear cell renal cell carcinoma (ccRCC) prognosis, and immunotherapy response. In current study, comprehensive bio-informative analysis was adopted to construct a TME-related lncRNA signature for immune checkpoint inhibitors (ICIs) and targeted drug responses in ccRCC patients.

Methods: The TME mRNAs were screened following the immune and stromal scores with the data from GSE15641, GSE29609, GSE36895, GSE46699, GSE53757, and The Cancer Genome Atlas (TCGA)-kidney renal clear cell carcinoma (KIRC).

Novel immune-related signature based on immune cells for predicting prognosis and immunotherapy response in clear cell renal cell carcinoma.

Background: Clear cell renal cell carcinoma (ccRCC) is the most common malignant tumor of the kidney and is characterized by poor prognosis. We sought to build an immune-related prognostic signature and investigate its relationship with immunotherapy response in ccRCC.

Methods: Immune-related genes were identified by ssGSEA and WGCNA.