Oxygen desaturation index, lowest arterial oxygen saturation and time spent below 90% oxygen saturation as diagnostic markers for obstructive sleep apnea.

Background: Obstructive sleep apnea (OSA) syndrome is associated with a high mortality, and blood oxygen indexes play an important role in evaluating this disease. The objective of this study was to explore the value of blood oxygen indexes, including minimum oxygen saturation (LSpO), oxygen reduction index (ODI) and time spent with oxygen saturation below 90% (TS 90%), as diagnostic markers for OSA syndrome.

Methods: In this retrospective study, 320 patients with OSA treated in Ningbo First Hospital from June 2018 to June 2021 were included and divided into mild, moderate, and severe groups according to the severity of the condition (n = 104, 92, and 124, respectively).

[Secretion and expression of E-selectin in nasal polyps].

Objective: To investigate the significance of E-selectin in nasal polyps.

Method: The E-selectin was measured by enzyme linked immunosorbent assay in 25 patients and 9 control cases from polyp tissue and normal inferior turbinates respectively. Meanwhile, the expression of E-selectin in these samples was studied with immunohistochemistry.