Publications by authors named "Huajin Tao"
CircRNA Circ_0001721 Promotes the Progression of Osteosarcoma Through miR-372-3p/MAPK7 Axis.
Cancer Manag Res
September 2020
Article Synopsis
- Osteosarcoma (OS) is a prevalent bone tumor, and the role of circular RNA circ_0001721 in its progression is yet to be understood, despite its known influence on various cancers.
- Researchers employed multiple techniques like qRT-PCR, glucose consumption tests, and transwell assays to analyze the expression of circ_0001721 and its impact on osteosarcoma cell behaviors, including proliferation and invasion.
- Results showed that circ_0001721 and MAPK7 levels are increased in OS tissues while miR-372-3p is decreased; knockdown of circ_0001721 reduced glycolysis and cancer cell activity, indicating that circ_0001721 acts as a sponge for miR-372-3