Publications by authors named "Huai-Jing Wang"

Article Synopsis
  • The study aimed to investigate how insulin-like growth factor-1 (IGF-1) affects the expression of specific mRNAs related to substance P and calcitonin gene-related peptide in nerve cells under stress from glutamate.
  • The researchers cultured dorsal root ganglion (DRG) neurons from rats and exposed them to glutamate with varying concentrations of IGF-1 to assess the impact on neuron health and gene expression.
  • Results indicated that IGF-1 not only prevented neuron damage caused by glutamate but also increased the mRNA levels of substance P and calcitonin gene-related peptide in a dose-dependent manner, suggesting a potential neuroprotective role for IGF-1.
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Objectives: To investigate whether butyrate increases substance P (SP) and calcitonin gene-related peptide (CGRP) release evoked by capsaicin from primary cultured dorsal root ganglion (DRG) neurons.

Methods: DRG was dissected out from embryonic 15-day-old Wistar rat and cultured as dissociate cells for 24 h then exposed to butyrate (0.01 mmol/L, 0.

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