Examining the prognostic and clinicopathological significance of GPX4 in human cancers: a meta-analysis.

Elevated levels of the enzyme GPX4 have been detected in tumor tissues, which may play a role in cancer progression. We did a meta-analysis of eight studies encompassing 1180 individuals to evaluate the importance of GPX4 in cancer, particularly in terms of prognosis and clinicopathological characteristics. Research results indicate that higher levels of GPX4 were linked to worse overall survival (OS) (HR = 1.

Lanthanide coordination polymers based on designed bifunctional 2-(2,2':6',2″-terpyridin-4'-yl)benzenesulfonate ligand: syntheses, structural diversity and highly tunable emission.

Seven novel lanthanide coordination polymers, [Eu(STP)(glu)] (1), [Ln(STP)(glu)]·4nHO [Ln = Er (2), Yb (3)], [Ln(STP)(1,3-bdc)]·0.5nHO [Ln = Tb (4), Yb (5)], and [Ln(STP)(1,2-bdc)] [Ln = Eu (6), Tb (7)] [NaSTP = sodium 2-(2,2':6',2″-terpyridin-4'-yl)benzenesulfonate, Hglu = glutaric acid, H(1,3-bdc) = benzene-1,3-dicarboxylic acid, H(1,2-bdc) = benzene-1,2-dicarboxylic acid], have been prepared under hydrothermal conditions and characterized by elemental analysis, IR and single-crystal X-ray diffraction. Compound (1) possesses a 2D layered structure based on 1D chains with STP and glu anions acting as bridges.

Structural investigation of one- and three-dimensional lanthanide(III) coordination polymers based on functionalized terpyridine carboxylate and aromatic dicarboxylate ligands.

Three series of lanthanide coordination polymers, namely catena-poly[[lanthanide(III)-μ-(benzene-1,2-dicarboxylato)-μ-[2-(2,2':6',2''-terpyridin-4'-yl)benzoato]] monohydrate], {[Ln(CHO)(CHNO)]·HO} or {[Ln(1,2-bdc)(L)]·HO}, with lanthanide (Ln) = dysprosium (Dy, 1), holmium (Ho, 2) and erbium (Er, 3), poly[bis(μ-benzene-1,3-dicarboxylato)bis[μ-2-(2,2':6',2''-terpyridin-4'-yl)benzoato]dilanthanide(III)], [Ln(CHO)(CHNO)] or [Ln(1,3-bdc)(L)], with Ln = gadolinium (Gd, 4), Ho (5) and Er (6), and poly[(μ-benzene-1,4-dicarboxylato)[μ-2-(2,2':6',2''-terpyridin-4'-yl)benzoato]lanthanide(III)], [Ln(CHO)(CHNO)] or [Ln(1,4-bdc)(L)], with Ln = Dy (7), Ho (8), Er (9) and ytterbium (Yb, 10), were synthesized under hydrothermal conditions and characterized by elemental analysis, IR and single-crystal X-ray diffraction. Compounds 1-3 possess one-dimensional loop chains with Ln(COO) units, which are extended into three-dimensional (3D) supramolecular structures by π-π interactions. Isostructural compounds 5 and 6 show 6-connected 3D networks, with pcu topology consisting of Ln(COO) units.

Sorcin induces gastric cancer cell migration and invasion contributing to STAT3 activation.

Gastric cancer (GC) is a globally occurring malignancy that is characterized by a high mortality rate due to a high tendency to metastasize and poor prognoses. Sorcin, as known as SRI, a soluble resistance-related calcium-binding protein, plays a significant role in multidrug resistance. Sorcin is related to the migration and invasion of cancer cells.

Promotional effect of nonalcoholic fatty liver disease on Gallstone disease: A systematic review and meta-analysis.

Background/aims: Growing evidence indicates that nonalcoholic fatty liver disease (NAFLD) and gallstone disease (GD) share the same risk factors, and that NAFLD may be associated with the occurrence of GD. However, overall results remain controversial. The aim of this study is to perform a meta-analysis to assess the relationship between GD and NAFLD.