Single-cell transcriptomes reveal the heterogeneity and microenvironment of vestibular schwannoma.

Background: Vestibular schwannoma (VS) is the most common benign tumor in the cerebellopontine angle and internal auditory canal. Illustrating the heterogeneous cellular components of VS could provide insights into its various growth patterns.

Methods: Single-cell RNA sequencing was used to profile transcriptomes from 7 VS samples and 2 normal nerves.