The impact of baseline calcified plaque volume on coronary rapid plaque progression by serial coronary computed tomography angiography in patients with type 2 diabetes.

Objectives: Patients with type 2 diabetes mellitus (T2DM) are susceptible to coronary artery disease (CAD), and coronary outcomes in these patients are heterogeneous. However, the impact of coronary plaque compositions on rapid plaque progression (RPP) in patients with T2DM has rarely been reported. This study aimed to investigate the association of coronary plaque compositions with rapid lesion volume progression in patients with T2DM.

[Genetic analysis of a Chinese patient with congenital disorders of glycosylation-If].

Objective: To explore the genetic basis for a Chinese patient with congenital disorders of glycosylation-If (CDG-If).

Methods: Whole exome sequencing (WES) was carried out for the patient.

Results: The patient, a 5-year-old girl, has featured severe mental retardation.

Mathematical model and nanoindentation properties of the claws of Cyrtotrachelus buqueti Guer (Coleoptera: Curculionidae).

Scanning electron microscopy (SEM) was used to observe the macroscopic, microscopic, and cross-sectional structures of the claws of Cyrtotrachelus buqueti Guer (Coleoptera: Curculionidae), and a mathematical model of a claw was used to investigate the structure-function relationships. To improve the quality of the SEM images, a non-local means (NLM) algorithm and an improved NLM algorithm were applied. After comparison and analysis of five classical edge-detection algorithms, the boundaries of the structural features of the claw were extracted based on a B-spline wavelet algorithm, and the results showed that the variable curvature of the beetle claw enhances its adhesion force and improves its strength.

Activity recognition using multiplex limited penetrable visibility graph.

To solve the dynamic problem of different activities in human activity recognition research, an activity recognition method based on a multiplex limited penetrable visibility graph is proposed. The 21 pressure values for each sampling are mapped to nodes in the first-layer network; then the average path length of nodes in the asynchronous periodic network is obtained, and the second-layer network used to explore different activities is built. Finally, the characteristic parameters and dynamic characteristics of different activities are explored and analyzed.

Mathematical Model and microCT-Based Kinematic Analysis of the Rostrum Mouthparts in Guer (Coleoptera: Curculionidae).

To uncover the chewing mechanism of Cyrtotrachelus buqueti Guer, a mathematical model was created and a kinematic analysis of its rostrum mouthparts was conducted for, to our knowledge, the first time. To reduce noise and improve the quality of scanning electron micrographs of the weevil's mouthparts, nonlocal means and integral nonlocal means algorithms were proposed. Additionally, based on a comparison and analysis of five classical edge detection algorithms, a multiscale edge detection algorithm based on the B-spline wavelet was used to obtain the boundaries of structural features.

[Analysis of prenatal phenotype and pathogenetic variant in a fetus with Papillorenal syndrome].

Objective: To determine the carrier rate of deafness-related genetic variants among 53 873 newborns from Zhengzhou.

Methods: Heel blood samples of the newborns were collected with informed consent from the parents, and 15 loci of 4 genes related to congenital deafness were detected by microarray.

Results: In total 2770 newborns were found to carry deafness-related variants, with a carrier rate of 5.

Clinical research on the dexmedetomidine applied for patient-controlled sedation during the lower limbs operation under combined spinal-epidural anesthesia.

To investigate the effect and safety of dexmedetomidine applied for patient-controlled sedation under combined spinal anesthesia. 150 cases who would be implemented lower limbs operations were randomly divided into patient-controlled sedation group (Group PCS) and control group (Group C) and 75 cases for each group. The ages of patients were between 18 and 65 years old and patients were with American Society of Anesthesiologists (ASA) or level.

[Effect of the treatment acceptance on the perinatal outcomes in women with subclinical hypothyroidism, positive thyroid gland peroxidase antibody in early pregnancy].

Objective: To investigate if women with subclinical hypothyroidism (SCH), positive thyroid gland peroxidase antibody (TPOAb) in early pregnancy accepted treatment or not had effect on perinatal outcomes.

Methods: 15 000 pregnant women who delivered in Women and Infants Hospital of Zhengzhou from January 1, 2013 to June 30, 2014 were recruited retrospectively. Among them, 2 042 women had SCH in early pregnancy.

Risk factors for early miscarriage among Chinese: a hospital-based case-control study.

Objective: To investigate the risk factors for early miscarriage among Chinese women.

Design: Hospital-based matched case-control study.

Setting: Academic medical center and maternal health hospital.

[Prevalence trend of neural tube defect in Zhengzhou city, 1996-2005].

Objective: To describe the prevalence trend and epidemiological characteristics of neural tube defects (NTDs) in perinatal in Zhengzhou city from 1996 to 2005.

Methods: Data collected from hospital were used to depict the epidemiology of NTDs in Zhengzhou. All perinatal fetuses born in hospitals had an access within 7 days after delivery.