Publications by authors named "Huafang Hou"
Article Synopsis
- The study focuses on developing new nomograms to predict the overall survival (OS) and cancer-specific survival (CSS) of colorectal cancer patients with unresectable liver metastasis after primary surgery, utilizing data from the SEER database.
- Using Cox regression, the research identified key prognostic factors, such as age, chemotherapy, and tumor characteristics, which significantly influence patient outcomes.
- The nomograms were found to offer better accuracy and predictive power compared to the traditional TNM classification, as demonstrated by various analytical methods including the C-index, ROC curves, and calibration curves, with validation confirming their effectiveness.
Transl Cancer Res
August 2023
Article Synopsis
- SFRP proteins are key regulators of Wnt signaling and play important roles in cell growth and cancer spread, but their functions in colorectal cancer (CRC) are still not well understood.
- Researchers used various databases to analyze the expression and impact of SFRP proteins in CRC, finding significant differences in expression and genetic changes among the SFRP family members.
- SFRP2 stands out as being linked to CRC prognosis and vital biological processes, with its suppression leading to reduced cancer cell growth and spread, suggesting it could be a new prognostic marker for CRC.
