IEEE J Biomed Health Inform
February 2025
In the field of gland segmentation in histopathology, deep-learning methods have made significant progress. However, most existing methods not only require a large amount of high-quality annotated data but also tend to confuse the internal of the gland with the background. To address this challenge, we propose a new semi-supervised method named DCCL-Seg for gland segmentation, which follows the teacher-student framework.
View Article and Find Full Text PDFRetinal vessel segmentation based on deep learning is an important auxiliary method for assisting clinical doctors in diagnosing retinal diseases. However, existing methods often produce mis-segmentation when dealing with low contrast images and thin blood vessels, which affects the continuity and integrity of the vessel skeleton. In addition, existing deep learning methods tend to lose a lot of detailed information during training, which affects the accuracy of segmentation.
View Article and Find Full Text PDFHigh throughput nuclear segmentation and classification of whole slide images (WSIs) is crucial to biological analysis, clinical diagnosis and precision medicine. With the advances of CNN algorithms and the continuously growing datasets, considerable progress has been made in nuclear segmentation and classification. However, few works consider how to reasonably deal with nuclear heterogeneity in the following two aspects: imbalanced data distribution and diversified morphology characteristics.
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