Novel Porous Starch Granules Fabricated Using Controlled Lipase-Amylase Treatments: Application as Delivery Systems and Resistant Starches.

Porous starch granules (PSGs) are promising biomaterials for the encapsulation, protection, and delivery of bioactive ingredients. In this study, a lipase treatment was first used to generate pores in native starch granules, and then α-amylase was used to enlarge these pores. Electron and fluorescence microscopy analysis showed that the lipase treatment exposed the starch molecules located below the lipid-rich regions on the starch granule surfaces, which increased the swelling of the granules in aqueous solutions.

Biomacromolecular carriers based hydrophobic natural products for potential cancer therapy.

Cancer is the second leading cause of death worldwide. It was estimated that 90 % of cancer-related deaths were attributable to the development of multi-drug resistance (MDR) during chemotherapy, which results in ineffective chemotherapy. Hydrophobic natural products plays a pivotal role in the field of cancer therapy, with the potential to reverse MDR in tumor cells, thereby enhancing the efficacy of tumor therapy.

Interaction between potassium iodide and bovine serum albumin, ovalbumin and lysozyme under different temperature induction.

In this study, the interaction between potassium iodide and protein molecules under different temperature induction was studied, taking potassium iodide (KI) and protein molecules as a model system. The effects of KI on protein conformation, size, surface charge, binding constant, and binding site were analyzed by fluorescence spectrum, infrared spectrum, and diffusing wave spectroscopy. The results revealed that bovine serum albumin (BSA)/ovalbumin (OVA) and I formed the 1: 1 complex and significantly affected the hydrodynamic radius and spatial structure.