Optical coherence tomography reveals a non-spasm pseudo-coronary artery stenosis: a case report and review of literature.

We described a case of angiographic stenosis that was highly suitable for stenting and it remained even after repeated intracoronary administration of nitroglycerin. However, optical coherence tomography showed the stenosis disappeared and the artery wall was smooth. It was therefore speculated that this was a just non-spasm pseudo-coronary artery stenosis.

[Association between 1019C/T polymorphism of Connexin 37 gene and restenosis after coronary stenting].

Objective: To assess the association between 1019C/T polymorphism of Connexin 37 (CX37) gene and susceptibility to restenosis after percutaneous coronary intervention (PCI) in ethnic Han Chinese patients from Wuxi.

Methods: Five hundred and thirty-two patients with coronary artery disease (CAD) who had undergone PCI underwent coronary angiography (CAG) in 3 months, and were divided into in stent restenosis (ISR) group (n=67) and no instent restenosis (NISR) group (n=465). Five hundred and one healthy individuals have served as the control group.

Association between C1019T polymorphism of the connexin37 gene and coronary heart disease in patients with in-stent restenosis.

Studies have shown that a C1019T polymorphism of the gene encoding the gap junction protein connexin37 is associated with coronary artery disease (CAD). The aim of the present study was to explore the association between the C1019T polymorphism in the connexin37 gene and CAD patients with in-stent restenosis (ISR). A total of 532 patients who had undergone coronary stenting and coronary angiography at least three months after the procedure were divided according to a clinical diagnosis standard into two groups which were ISR (n=67) and no in-stent restenosis (NISR; n=465) groups.

Effect of rosuvastatin on ROCK activity, endothelial function, and inflammation in Asian patients with atherosclerosis.

Background: HMG-CoA reductase inhibitors (statins) inhibit cholesterol biosynthesis, and also decrease the formation of isoprenoid intermediates required for the activation of Rho kinase (ROCK) pathway. ROCK pathway plays pivotal roles in cardiovascular diseases including arteriosclerosis. It has been implicated that inhibition of ROCK can reverse vascular dysfunction in humans with atherosclerosis.