Clinical Significance of a Novel Knee Joint Stability Assessment System for Evaluating Anterior Cruciate Ligament Deficient Knees.

Objective: To investigate the six degrees of freedom (6DOF) kinematics of anterior cruciate ligament (ACL) deficient knees during gait and to explore the clinical significance of a novel knee joint stability assessment system (Opti_Knee, Innomotion, Shanghai, China) in comparison with imaging and arthroscopic examination.

Methods: Three subjects diagnosed with ACL deficient knees on the basis of preoperative MRI and CT findings were subjected to treadmill gait analysis. Motion of both knees in 6DOF was measured and analyzed with an optical joint kinematics measurement system.

Biomechanics of single-tunnel double-bundle anterior cruciate ligament reconstruction using fixation with a unique expandable interference screw.

Background: Single-tunnel double-bundle (STDB) anterior cruciate ligament (ACL) reconstruction can restore biomechanical function and anatomic structure, but existing methods of graft fixation are not adequate. The aims of this study are to examine knee biomechanics after STDB reconstruction using a unique expandable interference screw for fixation.

Methods: The biomechanical parameters of six pairs of human cadaveric knee specimens were measured with the ACL intact, after ACL removal, and after STDB reconstruction using the interference screw or single-tunnel single-bundle (STSB) reconstruction.

[Features of the dual energy technique with dual-source computed tomography for anterior cruciate ligament injuries].

Objective: To explore the diagnostic value of the dual-energy technique with dual-source computed tomography (DSCT) for anterior cruciate ligament injuries.

Methods: The clinical data of 8 patients with arthroscopic results were retrospectively reviewed. All patients underwent two- and three-dimensional imaging by multiplanar reconstruction, volume rendering, and tendon mode on DSCT.

[Preparation of cisplatin-impregnated coral hydroxyapatite drug delivery system].

Objective: To prepare a cisplatin-impregnated coral-derived hydroxyapatite (CCHA) drug delivery system (DDS), and evaluate its inhibitory effect on human osteosarcoma cells U-2 OS, human breast cancer and prostatic carcinoma cells PC-3 in vitro.

Methods: The coral-derived hydroxyapatite (CHA) was manufactured by hydrothermal exchange and impregnated with cisplatin by vacuum freeze-drying techniques. The leaching solutions of this DDS was collected at different intervals in a course of 8 weeks and their inhibitory effect on the cells was tested in vitro by MTT assay.

[Results of 1310 knees of meniscal treatment evaluated by arthroscopy].

Objective: To evaluate results of 1310 knees of meniscal treatments by arthroscopy and to present good method of meniscal treatment.

Methods: Their age, traumatic mechanism and effects under arthroscopy were analysed in a series of 254 patients with meniscal injuries, there were 880 males and 374 females, the average of the patients was 25.5 years.

[The reason and prevention of upper cervical reoperations].

Objective: To discuss the reasons for the operation performed on 13 patients with upper cervical disease and to explore the management and prevention of upper cervical disease.

Methods: Thirteen patients with upper cervical disease were retrospectively reviewed. The reason for of reoperations on these patients were analyzed.

[Comparative clinical observation of the short-term bone fusion effect of composite biosynthetic bone and ilium auto-grafting].

Objective: To evaluate the short-term bone fusion after implantation of composite biosynthetic bone made of coralline hydroxyapatite composite (CHC) as a substitute for autologous bone grafting.

Methods: A clinical sequential trial was designed and the biosynthetic bone and the patient's ilium were respectively used in the treatment of femoral nonunions and interbody fusion. X-ray examinations were performed 10 weeks after the operations and the bone fusion was graded according to Lane-Sandhu's method.

[Biomechanical response of the femur-tibia model under impact loading of the body weight].

Objective: To study the biomechanical response and the role of articular surface on the femur-tibia model under impact loading of the body weight.

Methods: A three-dimensional finite element (FE) model of the femur-tibia composite was reconstructed using the image data of the knee joint of Virtual Chinese Human No.1 Male, and FE calculation was performed to simulate the impact of the body weight on the knee joint while walking.