Comprehensive analysis of competitive endogenous RNAs network associated with head and neck squamous cell carcinoma.

Long non-coding RNAs (lncRNAs) can regulate gene expression directly or indirectly through interacting with microRNAs (miRNAs). However, the role of differentially expressed mRNAs, lncRNAs and miRNAs, and especially their related competitive endogenous RNAs (ceRNA) network in head and neck squamous cell carcinoma (HNSCC), is not fully comprehended. In this paper, the lncRNA, miRNA, and mRNA expression profiles of 546 HNSCC patients, including 502 tumor and 44 adjacent non-tumor tissues, from The Cancer Genome Atlas (TCGA) were analyzed.

Expression of RUNX2 and MDM21 in rats with periodontitis under chronic intermittent hypoxia.

Objective: To discuss the expression of RUNX2 and MDM21 in rats with periodontitis under the chronic intermittent hypoxia.

Methods: A total of 32 SD healthy rats were randomly divided into four groups, with 8 rats in each group. The molecular biological techniques of immunohistochemistry, RT-PCR and Western blotting were employed to detect the effect of different hypoxia time (0, 6, 12, 24 and 48 h) and different concentrations of hypoxia (0.

Responses of distraction regenerate to high-frequency traction at a rapid rate.

Background: Continuous traction is capable of creating an optimal biological environment for bone healing which may finally compensate for the rapid distraction rate in distraction osteogenesis. This study was designed to investigate the response of distraction callus to continuous distraction at a rapid rate using a rabbit model of mandibular lengthening.

Methods: Thirty adult New Zealand white rabbits were randomly assigned to the intermittent (1 step/d) or continuous distraction (8 steps/s) group, with 15 in each.

Comparison of gene expression of tissue inhibitor of matrix metalloproteinase-1 between continuous and intermittent distraction osteogenesis: a quantitative study on rabbits.

Background: Distraction osteogenesis is a controlled surgical procedure that initiates a regenerative process and uses mechanical strain to enhance the biological responses of the injured tissues to create new bone. To explore the effect of high-frequency mechanical traction on the expression of tissue inhibitor of matrix metalloproteinase-1 (TIMP-1), we compared the gene expression of TIMP-1 between continuous and intermittent distraction osteogenesis using a rabbit model of mandibular lengthening.

Materials And Methods: Forty adult New Zealand white rabbits were randomly assigned to the intermittent and continuous distraction groups.

3-[(5-Methyl-furan-2-yl)methyl-ene]-1,5-dioxaspiro-[5.5]undecane-2,4-dione.

There are two crystallographically independent mol-ecules in the asymmetric unit of the title compound, C(15)H(16)O(5). In each, the 1,3-dioxane ring is in an envelope conformation with the C atom common to the cyclo-hexane ring forming the flap. The dihedral angles between the five essentially planar [maximum deviations from the least-squares planes of 0.

(Z)-3-(3-Phenyl-allyl-idene)-1,5-dioxa-spiro-[5.5]undecane-2,4-dione.

In the title compound, C(18)H(18)O(4), the 1,3-dioxane ring adopts a distorted envelope conformation with the C atom common to the cyclo-hexane ring forming the flap. In the crystal, inversion dimers linked by pairs of C-H⋯O hydrogen bonds occur.

Bis[2-acetyl-3-methyl-pyrazine (2-hydroxy-benzo-yl)hydrazonato]zinc(II) monohydrate.

In the title compound, [Zn(C(14)H(13)N(4)O(2))(2)]·H(2)O, the Zn(II) centre is six-coordinated by four N and two O donors of two 2-acetyl-3-methyl-pyrazine (2-hydroxy-benzo-yl)hydrazonate ligands, and forms a distorted octa-hedral structure.

{2,2'-[4-Methyl-4-aza-heptane-1,7-diylbis(nitrilo-methyl-idyne)]diphenolato}zinc(II).

In the title compound, [Zn(C(21)H(25)N(3)O(2))], the Zn(II) atom is five-coordinate from three N donor atoms and two O donor atoms of the dianion ligand in a distorted trigonal-bipyramidal arrangement. Three methyl-ene groups of the ligand are disordered over two orientations in a 0.555 (6):0.

N-(1-Naphth-yl)acetoacetamide.

The title compound, C(14)H(13)NO(2), exists in the keto form. An N-H⋯O hydrogen bond helps to establish the packing.

[Relevance of FcgammaRIIIb genotype, IgG G2m(23) factor to the susceptibility of aggressive periodontitis].

Objective: To investigate the polymorphism of FcgammaRIIIb genotype, IgG G2m(23) factor and their associations with the susceptibility to aggressive periodontitis.

Methods: DNA of white blood cells and serum from 21 aggressive periodontitis patients and 26 healthy controls was extracted. Genotype of FcgammaRIIIb and phenotype of G2m(23) factor was determined by allele-specific PCR and dot immunobinding assay respectively.