The effects of simultaneous operation on dissociated vertical deviation with horizontal and torsional strabismus.

Aim: To investigate the therapeutic effects of simultaneous horizontal and vertical operations on dissociated vertical deviation (DVD) associated with other deviations.

Methods: Forty-five cases of DVD with horizontal and torsional strabismus underwent combined operation were collected retrospectively. All clinical records were analyzed.

Lymphocyte infiltration and activation in iris-ciliary body and anterior chamber of mice in corneal allograft rejection.

Aim: To investigate the infiltration and activation of lymphocyte in iris-ciliary body and anterior chamber after allogenic penetrating keratoplasty (PK), for further revealing the role of iris-ciliary body in corneal allograft immune rejection.

Methods: In the mice models of PK, BALB/C mice received orthotopic isografts (n =35) or C57BL/6 donor allografts (n =25). Grafts were examined daily for 3 weeks by slit-lamp microscopy and scored for opacity.

[Palisade endings of extraocular muscles in eyes with congenital nystagmus].

Objective: To evaluate the morphology, distribution and function of palisade endings (PE) in human extraocular muscles (EOM), and observe the alterations in eyes with congenital nystagmus (CN). The etiology and pathogenesis of CN were also investigated.

Methods: It was a experimental study.

[The preliminary study of establishing animal model of chronic allograft dysfunction after penetrating keratoplasty].

Objective: To establish a murine model of chronic corneal allograft dysfunction (CCAD) after penetrating keratoplasty (PK).

Methods: Experimental study. PK model in mice: Semiallogeneic CB6F1 mice were obtained from matching of female BALB/c and male C57BL/6 mice.

Minimally invasive botulinum toxin type A injection from the ocular surface to extraocular muscles.

Aim: To investigate a new, safe and effective injection method for strabismus patients. Botulinum toxin type A (BTXA) was injected by pulling the extraocular muscles with a minimally-invasive technique into the ocular surface, and it was ensured that the extraocular muscles was maintained in the suspended state.

Methods: A total of 32 patients with different types of strabismus were treated at our institution from February to October 2010.

[Experimental study of low molecular weight heparin drug delivery system for prevention of posterior capsular opacification in rabbit eyes].

Objective: To investigate the safety and efficacy of low-molecular-weight heparin drug delivery system (LMWH DDS) for prevention of posterior capsular opacification (PCO) in rabbit eyes.

Methods: (1) To prepare the LMWH DDS by freeze-drying way with Polylactic-co-glycolic acid (PLGA) as the carrier, and evaluate its release properties in vitro. (2) Fifty New Zealand albino rabbits (50 eyes) undergoing phacoemulsification were equally divided into five groups: receiving normal saline eye drops (group A), 3 different dose (1 mg, 0.

[Ultrastructure changes in chronic corneal allograft dysfunction after penetrating keratoplasty].

Objective: To study the ultrastructure changes of failed graft caused by chronic corneal allograft dysfunction (CCAD) after penetrating keratoplasty (PK), and to reveal the possible mechanism of these changes.

Methods: In CCAD group, corneas of 12 patients fulfilling the diagnostic criteria for CCAD who underwent repeated PK operation were studied. The average interval of these 12 patients between two PK operations was 69 months.