Publications by authors named "Hua-Peng Hao"
Kaohsiung J Med Sci
December 2023
Article Synopsis
- The study investigates how DYRK1a influences ferroptosis (a type of cell death) in heart cells during damage caused by blocked blood flow and subsequent restoration (MIRI).
- Transfections of H9c2 cells with DYRK1a inhibitors led to improved cell survival and lower indicators of oxidative stress and ferroptosis.
- In a rat model for MIRI, suppression of DYRK1a further confirmed its role in worsening heart cell injury and ferroptosis during ischemia-reperfusion events.
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