Liver transplantation in a child with sclerosing cholangitis due to Langerhans cell histiocytosis: a case report.

Background: Langerhans cell histiocytosis (LCH) is a systemic neoplasia with diverse clinical manifestations, predominantly affecting bone and skin. However, in children, LCH presenting primarily with cholestasis is rare.

Case Summary: We present the case of a 22-month-old boy who was admitted to our hospital with a history of intermittent fever and abdominal distension for over 2 months, and jaundice for over 1 month.

Clinical Characteristics of H1N1 Influenza A-Associated Mild Encephalopathy with Reversible Splenial Lesion: 4 Pediatric Cases.

Objective: Mild encephalopathy with reversible splenial lesion (MERS) is associated with a variety of infections and anti-epileptic drug withdrawal. Here we report the clinical characteristics of H1N1 influenza A-associated MERS based on our experience of four pediatric cases.

Methods: A detailed retrospective analysis of four patients with H1N1 influenza A-associated MERS was performed at Guangzhou Women and Children's Medical Center.

The role of the lactadherin in promoting intestinal DCs development in vivo and vitro.

Lactadherin, as one of the immune components in the breast milk, might play a role in the intestinal immune system of newborn. Therefore, we investigated the effect of lactadherin-feeding in early time on the development of intestinal immune system compared with naturally rearing and artificially rearing (non-lactadherin). In the present study, we observed that the Peyer's Patches (PP) from the pups of artificially reared group with lactadherin added were characterized by an excess of OX62(+)CD4(+)SIRP(+) DC cells and a higher expression of CD3(+)CD4(+)CD25(+)T cells.

Morphology and ontogeny of dendritic cells in rats at different development periods.

Aim: To study the morphology and ontogeny of dendritic cells of Peyer's patches in rats at different development periods.

Methods: The morphometric and flow cytometric analyses were performed to detect all the parameters of villous-crypts axis and the number of OX62(+)DC, OX62(+)CD4(+)SIRP(+)DC, and OX62(+)CD4(-)SIRP(-)DC in the small intestine in different groups of rats. The relationship between the parameters of villous-axis and the number of DC and DC subtype were analyzed.