Publications by authors named "Hua-Lei Zhai"
Aim: To review the indications of penetrating keratoplasty (PK) and anterior lamellar keratoplasty (ALK) at Qingdao Eye Hospital, Shandong Eye Institute, Qingdao, China, from 2010 to 2017.
Methods: The data of all patients undergoing PK or ALK from January 2010 to December 2017 was retrospectively reviewed, with the indications during 2010-2013 and 2014-2017 compared.
Results: A total of 1869 eyes were included, among which 1405 eyes (75.
Aim: To analyze indications and reasons for failure of anterior lamellar keratoplasty (ALK).
Methods: The clinical records were retrospectively reviewed. Main outcome measures included indications for ALK and reasons for failure of ALK.
Aim: To compare the clinical characteristics of infectious keratopathy in type 2 diabetes mellitus (T2DM) and non-diabetes mellitus (NDM) and to investigate risk factors for infectious keratopathy in T2DM patients.
Methods: Totally 230 patients with T2DM and 168 with NDM diagnosed as infectious keratopathy were hospitalized at Qingdao Eye Hospital from 2001 to 2015. Data including sex, age, occupation, season, smoking and alcohol consumption habits, duration between onset and treatments, duration of hospitalization were collected.
[The roles of gelatinases in pathological changes of fungal keratitis in experimental rabbits].
Zhonghua Yan Ke Za Zhi
September 2007
Objective: To study the roles of gelatinases, including matrix metalloproteinase (MMP)-2 and MMP-9, in pathological changes of fungal keratitis in rabbits.
Methods: Eighty New Zealand albino rabbits were randomly and equally divided into 4 groups, 3 of them were test groups, with Fusarium solani, Aspergillus fumigatus, and Candida albicans inoculated onto the right corneas, respectively. In the other group, sterile saline was injected onto the right corneas and was used as the control group.
[Penetrating keratoplasty for treatment of fungal keratitis with corneal perforation].
Zhonghua Yan Ke Za Zhi
November 2005
Objective: To evaluate the outcome of penetrating keratoplasty (PKP) for the treatment of fungal keratitis with corneal perforation.
Methods: 40 patients (40 eyes) with corneal perforation secondary to fungal keratitis underwent PKP at Qingdao Eye Hospital from 1994 to 2003. The follow-up ranged from 6-24 months.