[Allergen Analysis of 4622 Children with Allergic Diseases in Shaanxi Province].

Objective: To study the distributional characteristics of allergens in children with allergic diseases in Shaanxi province.

Methods: A total of 4 622 children diagnosed with allergic diseases in the Asthma Center, Department of Pediatrics, Xijing Hospital from March 2015 to February 2019 were selected. Serum allergen-specific immunoglobulin E (sIgE) of 19 common kinds of allergens were examined with enzyme-linked immunosorbent assay (ELISA).

Protocatechuic acid inhibits TGF-β1-induced proliferation and migration of human airway smooth muscle cells.

Protocatechuic acid (3, 4-dihydroxybenzoic acid, PCA) is a major metabolite of anthocyanins and was reported to possess anti-allergic response. However, the effects of PCA on airway smooth muscle cells (ASMCs) proliferation and migration remain unclear. Therefore, this study aims to investigate the effects of PCA on proliferation and migration of ASMCs.