- This study explored how Fuzheng Huayu Tablets (FZHY) affect macrophage polarization in treating liver fibrosis, using advanced techniques like single-cell transcriptome sequencing and various experimental approaches.
- Researchers gathered gene datasets related to liver fibrosis and macrophage polarization from multiple databases, creating a protein-protein interaction (PPI) network to identify key proteins involved.
- The study used a carbon tetrachloride-induced mouse model of liver fibrosis to analyze liver tissue pathology and measure various protein and enzyme levels, confirming the impact of macrophage polarization on liver fibrosis treatment.