Publications by authors named "Hua-Gang Yang"
Article Synopsis
- Staphylococcus aureus protein A (SPA) disrupts bone formation by inducing apoptosis in osteoblasts and affects the differentiation of bone marrow-derived mesenchymal stem cells (BMSCs).
- Researchers identified 321 differentially expressed genes (DEGs) from SPA-interfered BMSCs and established a protein-protein interaction (PPI) network, identifying 6 potential biomarkers (Cenpf, Kntc1, Nek2, Asf1b, Troap, Kif14) that differentiate between normal and SPA-interfered BMSCs.
- The study revealed that the identified biomarkers are primarily involved in pyrimidine metabolism and showed significantly lower expression levels in the SPA-interfered group,
