Xanthan gum/ZrMOF biodegradable gel fertilizer: Sustainable water retention and crop growth.

To address the problems of ecological pollution and food safety caused by the excessive use of chemical fertilizers in modern agriculture, it has become a hot topic of current research to develop novel low-cost, biodegradable, and efficient gel slow-release fertilizers. Herein, using xanthan gum and ZrMOF as raw materials, urea as a nutrient, acrylic acid and itaconic acid as co-monomers, a novel ZrMOF gel slow-release fertilizer (ZrMOF@CpM) was prepared by free radical copolymerization. After being characterized, its swelling and water retention properties and slow-release behavior were investigated.

Association of triglyceride-glucose index and diabesity: evidence from a national longitudinal study.

Background: Diabesity, a co-occurrence of diabetes and obesity, is a growing public health concern globally. The triglyceride-glucose (TyG) index, a surrogate marker of insulin resistance, has been associated with various metabolic disorders. This study aimed to investigate the association between TyG index and new-onset diabesity in a national longitudinal study.

Development and validation of a psychotherapy change motivation scale.

Objective: Develop a Psychotherapy Change Motivation Scale (PCMS) with robust psychometric properties.

Method: A literature review, semi-structured interviews, and expert evaluation were used to draft the scale. The scale was administered to participants receiving psychological counseling or therapy at specialized hospital psychological intervention centers, university mental health education centers, and social psychological counseling agencies using convenience sampling.

Acinetobacter indicus coharboring tet(X6) and bla isolated from slaughterhouse waste.

Objectives: Acinetobacter indicus is an important pathogen of nosocomial infection. The purpose of this study was to analyze the resistance and transmission of A. indicus strain AIBD14 isolated from slaughterhouse environment.

Molecular networking and Paterno-Büchi reaction guided glycerides characterization and antioxidant activity assessment of Ganoderma lucidum spore oil.

Ganoderma lucidum spore oil (GLSO) is a dietary supplement, with glycerides (GLs) recognized as its important active component. However, comprehensive profiling and accurate structural characterization of GLs in GLSO remain underexplored. In this study, 59 GLs from GLSO were identified by ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF MS) and molecular networking (MN).

First preclinical SPECT/CT imaging and biodistribution of [Er]ErCl and [Er]Er-PSMA-617.

Background: Er (t = 10.4 h, E = 47.1 keV (59.

The safety profile of azithromycin in pediatrics: a pharmacovigilance disproportionality analysis.

Aim: To mine and analyze adverse drug events (ADEs) signals of azithromycin use in children in the real world to inform the safety assessment of azithromycin use in children.

Methods: ADE reports from the FDA Adverse Event Reporting System (FAERS) involving children (0-17 years) with azithromycin as the primary suspected drug from 2004 to early 2024 were extracted. ADEs were categorized using MedDRA, and signal detection was conducted using Reporting Odds Ratio (ROR) and Proportional Reporting Ratio (PRR).

Meta-Analysis of the Efficacy of Risperidone Treatment in Patients with First-Episode Schizophrenia.

Introduction: First-episode schizophrenia is a prevalent psychiatric disorder with a complex etiology. This meta-analysis evaluates the efficacy of risperidone in treating patients with first-episode schizophrenia.

Methods: A literature search was conducted to identify studies on the efficacy of risperidone for first-episode schizophrenia.

Single-cell RNA-seq reveals as a prognostic biomarker in low-grade endometrial stromal sarcoma.

Background: Low-grade endometrial stromal sarcoma (LG-ESS) is a rare uterine malignancy characterized by its complex tumor microenvironment (TME) and high recurrence rates, posing challenges to accurate prognosis and effective treatment. Identifying prognostic biomarkers is essential for improving patient stratification and guiding therapeutic strategies.

Methods: Using single-cell transcriptome analysis combined with H&E and multiplex immunofluorescence staining, we identified a subpopulation of tumor cells in LG-ESS and further validated the association of this subpopulation and its characteristic genes with LG-ESS prognosis by molecular characterization and bulk transcriptome data.

Radiomics and radiogenomics: extracting more information from medical images for the diagnosis and prognostic prediction of ovarian cancer.

Ovarian cancer (OC) remains one of the most lethal gynecological malignancies globally. Despite the implementation of various medical imaging approaches for OC screening, achieving accurate differential diagnosis of ovarian tumors continues to pose significant challenges due to variability in image performance, resulting in a lack of objectivity that relies heavily on the expertise of medical professionals. This challenge can be addressed through the emergence and advancement of radiomics, which enables high-throughput extraction of valuable information from conventional medical images.

Gut Microbiota, Circulating Metabolites and Risk of Endometriosis: A Two-Step Mendelian Randomization Study.

Epidemiological studies and animal models have suggested a possible link between gut microbiota (GM), circulating metabolites, and endometriosis (EMs) pathogenesis. However, whether these associations are causal or merely due to confounding factors remains unclear. We conducted a two-sample and two-step Mendelian randomization (MR) study to elucidate the potential causal relationship between GM and EMs, and the mediating role of circulating metabolites.

The causality between gut microbiota and endometriosis: a bidirectional Mendelian randomization study.

Background: Observational studies and animal experiments had suggested a potential relationship between gut microbiota abundance and pathogenesis of endometriosis (EMs), but the relevance of this relationship remains to be clarified.

Methods: We perform a two-sample bidirectional Mendelian randomization (MR) analysis to explore whether there is a causal correlation between the abundance of the gut microbiota and EMs and the direction of causality. Genome-wide association study (GWAS) data ukb-d-N80, finn-b-N14-EM, and MiBinGen were selected.

Tackling the Activity Trend of Metal-Loaded Metal Nitride Catalysts for NH Synthesis by a First-Principles Microkinetic Study.

Ammonia (NH) is one of the most widely produced chemicals globally, primarily synthesized through the Haber-Bosch process, which requires high temperatures and pressures. Dual-site catalysts can activate N and H at spatially separated sites, enabling efficient NH synthesis under milder conditions. Despite the rapid experimental progress of the dual-site catalysts (e.

LLGL2 targets the Hedgehog signaling pathway to influence malignant progression of endometrial cancer.

Background: Endometrial cancer (EC) is a malignant tumor of the endometrial epithelium, with endometrial adenocarcinoma being the most common type. It has a good overall prognosis, but recurrence and metastasis are often associated with poorer outcomes. LLGL2 is closely linked to tumorigenesis; however, its in endometrial carcinoma is unknown.

Structure-Dependent, Switchable Alder-Ene/[2π + 2σ] Cycloadditions of Vinyl Bicyclo[1.1.0]butanes with α-Ketoesters Enabled by Palladium Catalysis.

A structure-dependent, palladium-catalyzed switchable alder-ene/[2π + 2σ] cycloaddition of VBCBs with α-ketoesters has been reported. A variety of cyclobutenes and 2-oxabicyclo[2.1.

Soot particle morphology and polycyclic aromatic hydrocarbons formation molecular dynamics during diffusion combustion of three pentanol biofuels.

Soot particles constitute a major pollutant in engine diffusion combustion, posing a serious threat to human health and the atmospheric environment. The employment of carbon-neutral biofuel, pentanol, in engines contributes to reducing soot emissions; however, its effectiveness is contingent upon the position of the OH functional group. This work investigated the soot morphology and microstructural parameters evolution of three pentanol isomers, and explored the influence mechanism of OH functional group positional isomerism on the entire process of PAHs formation at the atomic level.

[Retracted] MicroRNA‑195‑5p inhibits the progression of hemangioma via targeting SKI.

[This retracts the article DOI: 10.3892/etm.2021.

Abdominal fat accumulation increases the risk of high blood pressure: evidence of 47,037 participants from Chinese and US national population surveys.

Aims: This study aims to ascertain whether abdominal fat accumulation evaluated by waist circumference increases the risk of hypertension using the nationwide population.

Methods: We enrolled 47,037 participants from the China Health and Nutrition Survey (CHNS), China Health and Retirement Longitudinal Study (CHARLS), and National Health, and Nutrition Examination Survey (NHANES). The adjusted logistic regression model was used to examine the relationship between waist circumference and prevalent hypertension.

The effect of a distorted MO octahedral unit on the activity and stability for the oxygen evolution reaction.

Metal oxides have garnered significant attention in the oxygen evolution reaction (OER), where a distorted MO octahedral unit has a marked impact on their performance. This study introduces the distortion coefficient to quantify the MO distortion composed of its volume and shape, and reports the effect of MO distortion on the activity and stability in rutile metal oxides for the OER. This provides a fundamental understanding for designing effective MO active units for the OER.

Diosgenin Mediated JAK/STAT Signal Channel Improving SD Rat Renal Ischemia-Reperfusion.

Objective: To explore the mechanism of action of diosgenin and JAK/STAT in SD rat renal ischemia-reperfusion (I/R) injury.

Method: A renal I/R injury model was established, rat was divided into four groups: control group, sham surgery group, I/R model group, and diosgenin pretreatment group. 48 hours after the completion of modeling, blood was collected for testing of SCr, BUN, and Kim-1.

Impact of body mass index on outcomes of cervical cerclage: a systematic review and meta-analysis.

Introduction: The purpose of the review was to examine the impact of maternal body mass index (BMI) on outcomes of cervical cerclage for cervical insufficiency.

Methods: This prospectively registered review (CRD42024512436) searched PubMed, Embase, Scopus, and Web of Science for comparative studies published before 6th March 2024. Maternal and neonatal outcomes of females undergoing cerclage were compared based on BMI.