Beneficial Effects of FEC on an In-Situ Polymerized Deep Eutectic Electrolyte for Solid-State Batteries.

Eutectic-based polymer electrolytes have emerged as promising solid electrolytes because of their ionic liquid-like properties, while modifications are essential to further increase their ionic conductivity at room temperature and solve their compatibility with lithium anode. In this work, an in situ polymerized composite electrolyte is modified by the addition of fluoroethylene carbonate (FEC) whose beneficial effect is systematically investigated in different contents. Poly(ethylene glycol) diacrylate (PEGDA), deep eutectic solvent (LiTFSI:-methylacetamide = 1:3), and alumina fiber work as the monomer, solvent, and three-dimensional skeleton, respectively.

GRINA alleviates hepatic ischemia‒reperfusion injury-induced apoptosis and ER-phagy by enhancing HRD1-mediated ATF6 ubiquitination.

Background & Aims: Hepatic ischemia‒reperfusion injury (HIRI) is a critical complication of liver surgery and transplantation that contributes significantly to severe organ failure. GRINA, a calcium-regulating endoplasmic reticulum (ER) protein, plays an essential role in controlling the unfolded protein response; however, its role in HIRI remains unclear. The aim of this study was to investigate the function of GRINA in HIRI and explore its potential as a therapeutic target.

Maternal exposure to bisphenol A induces congenital heart disease through mitochondrial dysfunction.

Congenital heart disease (CHD) represents a major birth defect associated with substantial morbidity and mortality. Although environmental factors are acknowledged as potential contributors to CHD, the underlying mechanisms remain poorly understood. Bisphenol A (BPA), a common endocrine disruptor, has attracted significant attention due to its widespread use and associated health risks.

Research Progress on the Chemical Constituents and Pharmacological Effects of Thunb and a Predictive Analysis of Quality Markers.

() is widely used in respiratory disease control as an important heat-clearing and detoxifying traditional Chinese medicine. It effectively clears away heat and toxins, eliminates carbuncles, and drains pus, and it is diuretic and detoxicating. The aim of this study is to review the botany, chemical composition, pharmacological effects, and quality control of to establish a better-quality evaluation system.

Learning Dendritic-Neuron-Based Motion Detection for RGB Images: A Biomimetic Approach.

In this study, we designed a biomimetic artificial visual system (AVS) inspired by biological visual system that can process RGB images. Our approach begins by mimicking the photoreceptor cone cells to simulate the initial input processing followed by a learnable dendritic neuron model to replicate ganglion cells that integrate outputs from bipolar and horizontal cell simulations. To handle multi-channel integration, we utilize a nonlearnable dendritic neuron model to simulate the lateral geniculate nucleus (LGN), which consolidates outputs across color channels, an essential function in biological multi-channel processing.

Performance of the 2023 diagnostic criteria for MOGAD: real-world application in a Chinese multicenter cohort of pediatric and adult patients.

Background: The clinical phenotypes of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) have been found to overlap with several other diseases. The new criteria proposed in 2023 were designed to better identify the disease but require validation across various populations to ascertain its clinical utility. We aimed to investigate the diagnostic performance in phenotypically diverse patients.

Multipath joint ablation strategy for focal atrial tachycardia originating from patent foramen ovale: a case report.

Introduction: Focal atrial tachycardia (FAT) is predominant in the pediatric population. Recent research has identified cases of sustained FAT originating from the interatrial septum (IAS); a subset of cases presents a unique challenge, with foci originating from the peri-patent foramen ovale (peri-PFO), requiring specialized management during catheter ablation. Here, we present a rare case of peri-PFO-associated FAT that resulted in tachycardia-related cardiomyopathy and propose a comprehensive multipath joint strategy for the successful treatment of PFO-associated FAT.

Relationship Between Carotid Artery Remodeling Characteristics and Early Carotid Atherosclerosis: An Ultrasonographic Multicenter Study.

Objectives: This study analyzed carotid artery remodeling characteristics in early carotid atherosclerosis (ECAS).

Methods: The 1021 participants were evaluated using ultrasonography and categorized into three groups: Group A, 391 participants with increased intima-media thickness (IMT); Group B, 300 participants with atherosclerotic plaque only on the carotid bulb (CB); and the control group (330 participants). The ratios of the diameters in the CB to those in the common carotid artery (D) and internal carotid artery (D) were defined as carotid index1 (CI) and 2 (CI).

Nomogram for prognosis prediction in metastatic pancreatic cancer patients undergoing intra-arterial infusion chemotherapy: incorporating immune-inflammation scores and coagulation indicators.

Background: Pancreatic cancer is one of the most malignant tumors with an inferior prognosis. This study aims to determine the prognostic significance of immune-inflammatory scores and coagulation indices in patients with metastatic pancreatic cancer(MPC) and develop a predictive nomogram.

Methods: This study retrospectively analyzed the clinical data of 384 patients with MPC who underwent intra-arterial infusion chemotherapy (IAIC).

Analysis of longitudinal social media for monitoring symptoms during a pandemic.

Objective: Current studies leveraging social media data for disease monitoring face challenges like noisy colloquial language and insufficient tracking of user disease progression in longitudinal data settings. This study aims to develop a pipeline for collecting, cleaning, and analyzing large-scale longitudinal social media data for disease monitoring, with a focus on COVID-19 pandemic.

Materials And Methods: This pipeline initiates by screening COVID-19 cases from tweets spanning February 1, 2020, to April 30, 2022.

Association between serum vitamin D and depression among non-alcoholic fatty liver disease.

Background And Objectives: While previous population-based studies have suggested a link between serum vitamin D levels and depression in individuals with non-alcoholic fatty liver disease (NAFLD), the exact correlation between serum vitamin D and depression among NAFLD patients remains controversial and disputed. Thus, we conducted this study to evaluate the relationship between serum vitamin D and depression in NAFLD participants diagnosed via transient elastography.

Methods And Study Design: This cross-sectional study was extracted from the latest NHANES 2017-2018 dataset.

Sodium tanshinone IIA sulfonate alleviates fetal growth restriction by mediating aquaporin-3 expression in placental trophoblast cells.

Fetal growth restriction (FGR) is characterized by the inability of the fetus to achieve its growth potential due to pathological factors, most commonly impaired placental trophoblast cell function. Currently, effective prevention and treatment methods of FGR are limited. We aimed to explore the pathogenesis of FGR and provide potential strategies for mitigating its occurrence.

Serum autoantibody-based biomarkers for prognosis in early-stage lung cancer patients with surgical resection.

Background: Lung cancer is the cancer with the highest morbidity and mortality in the world. With the increasing diagnosis rate of patients with early-stage lung cancer, surgery treatment becomes an option for more patients. However, there is a lack of effective indicators to assess the risk of recurrence after lung cancer surgery.

Arsenic trioxide preconditioning attenuates hepatic ischemia- reperfusion injury in mice: Role of ERK/AKT and autophagy.

Background: Arsenic trioxide (ATO) is indicated as a broad-spectrum medicine for a variety of diseases, including cancer and cardiac disease. While the role of ATO in hepatic ischemia/reperfusion injury (HIRI) has not been reported. Thus, the purpose of this study was to identify the effects of ATO on HIRI.

Application of Submandibular Intubation as Alternative to Elective Short-Term Tracheotomy for Particular Cases of Oral and Maxillofacial Tumors Resection and Defects Reconstruction.

Objective: To describe the cases of oral and maxillofacial tumors (OMFT) resection and defects reconstruction under submandibular intubation (SMI) performed in our institution; secondly, to systematically review and analyze the characteristics of studies about SMI in oral and maxillofacial surgery to estimate the incidence rate of complication.

Method: Data related to all 6 patients included in this study were prospectively collected from November 2016 to November 2023. The tract for endotracheal tube was created by bluntly dissection from the submandibular area to the floor of mouth.

Cellulose filter paper immobilized acetylcholinesterase for rapid screening of enzyme inhibitors in Phyllanthus emblica L.

Acetylcholinesterase (AChE) is widely recognized as a promising therapeutic target enzyme for Alzheimer's disease (AD). The screening of AChE inhibitors (AChEIs) holds great significance for the treatment of AD. In this study, cellulose filter paper (CFP) -immobilized AChE was prepared and firstly applied to screening AChEIs from 30 % ethanol extract of Phyllanthus emblica L.

Effect of cerium-zirconium oxide-loaded red mud on the selective catalytic reduction of NO in downhole diesel vehicle exhaust.

Red mud (RM), an iron oxide-rich solid waste, shows potential as a catalyst for selective catalytic reduction in denitrification processes. This study investigates the catalytic performance and mechanism of metal-modified RM in reducing NO from diesel vehicle exhaust. Acid-washed RM catalysts were impregnated with varying ratios of cerium (Ce) and zirconium (Zr).

Regional disparities in PPCPs contamination of urban wastewater treatment plants: Unveiling influential factors and ecological effects.

This study investigates the discharge of pharmaceuticals and personal care products (PPCPs) from wastewater treatment plants (WWTPs) into natural waters, highlighting a significant correlation with regional human activities. Despite the complexity of assessing factors influencing PPCPs sources, it remains underexplored. By conducting an extensive literature review of seven categories of PPCPs in WWTPs across five typical regions of China, the study reveals both similarities and disparities in PPCPs composition.

Potential-resolved electrochemiluminescent immunoassay based on dual co-reactants regulation.

Multi-signal-based self-calibrating biosensors have become a research focus due to their superior accuracy and sensitivity in recent years. Herein, the potential-resolved differential ECL immunoassay based on dual co-reactants regulation was developed. Meso-tetra(4-carboxyphenyl)porphyrin (TCPP) functionalized zirconium dioxide (ZrO) composites (TCPP-ZrO) was first synthesized using TCPP as the luminophore and ZrO as the enhancer and stabilizer.

Lanthanide-polyoxometalate-based self-erasing luminescent hydrogels with time-dependent and resilient properties for advanced information encryption.

In such an era of information explosion, improving the level of information security is still a challenging task. Self-erasing luminescent hydrogels are becoming ideal candidates for improving the level of information security with simple encryption and decryption methods. Herein, a lanthanide-polyoxometalate-based self-erasing luminescent hydrogel with time-dependent and resilient properties was constructed through a covalent crosslinked network constructed with polyacrylamide and a non-covalent crosslinked network constructed with [2-(methacryloyloxy)ethyl]trimethyl ammonium chloride/NaDyWO, along with doping urease.

Identification of crucial extracellular genes as potential biomarkers in newly diagnosed Type 1 diabetes integrated bioinformatics analysis.

Purpose: In this study, we aimed to study the role of extracellular proteins as biomarkers associated with newly diagnosed Type 1 diabetes (NT1D) diagnosis and prognosis.

Patients And Methods: We retrieved and analyzed the GSE55098 microarray dataset from the Gene Expression Omnibus (GEO) database. Using R software, we screened out the extracellular protein-differentially expressed genes (EP-DEGs) through several protein-related databases.

Chinese Pangolin Changes Local Vertebrate Assemblages and Contributes to Their Interspecific Interactions by Burrowing and Revisitation.

The burrow microhabitats created by burrowing mammals, as a hotspot for biodiversity distribution in ecosystems, provide multiple critical resources for many other sympatric species. However, the cascading effects of burrow resources on sympatric animal community assemblages and interspecific interactions are largely unknown. During 2020-2023, we monitored 184 Chinese pangolin (Manis pentadactyla) burrows using camera traps to reveal the burrow utilization patterns of commensal species.

Sensitive characterization of complex chemical reactions in black garlic preparation based on on-line extraction electrospray ionization mass spectrometry.

Changes in chemical composition during food processing and handling are crucial for the alteration of food flavor and function, and accurate characterization of key chemical reaction pathways in complex food matrices is one of the core challenges in food chemistry research. Here, this study attempts to establish a strategy for sensitive characterization of chemical reactions during food processing based on on-line extraction electrospray ionization mass spectrometry (oEESI-MS). The process of making garlic into black garlic, a traditional global flavor food, was chosen as an exemplary research template.

18beta-glycyrrhetinic acid alleviates deoxynivalenol-induced hepatotoxicity by inhibiting GPX4-dependent ferroptosis.

Deoxynivalenol (DON), a mycotoxin that severely contaminates agri-food products can cause hepatotoxicity. Ferroptosis is an iron-dependent form of cell death, and the liver is an important organ for iron accumulation. 18beta-glycyrrhetinic acid (GA) has anti-ferroptosis and hepatoprotective effects.