A dual-stream model based on PRNU and quaternion RGB for detecting fake faces.

The forensic examination of AIGC(Artificial Intelligence Generated Content) faces poses a contemporary challenge within the realm of color image forensics. A myriad of artificially generated faces by AIGC encompasses both global and local manipulations. While there has been noteworthy progress in the forensic scrutiny of fake faces, current research primarily focuses on the isolated detection of globally and locally manipulated fake faces, thus lacking a universally effective detection methodology.

Clinical Characteristics and Risk Factors for Multidrug-Resistant Complex Bacteremia in a Chinese Tertiary Hospital: A Decade Review (2013-2022).

Objective: This study aimed to analyze the antimicrobial resistance profiles, clinical characteristics and risk factors of bacteremia caused by complex (ECC) strains.

Methods: We retrospectively collected clinical data from patients diagnosed with ECC bacteremia between 2013 and 2022 in a tertiary hospital in Jiangsu. Subgroup analyses were performed based on multidrug resistance (MDR), nosocomial acquisition, polymicrobial bacteremia, and mortality.

Multiomic machine learning on lactylation for molecular typing and prognosis of lung adenocarcinoma.

To integrate machine learning and multiomic data on lactylation-related genes (LRGs) for molecular typing and prognosis prediction in lung adenocarcinoma (LUAD). LRG mRNA and long non-coding RNA transcriptomes, epigenetic methylation data, and somatic mutation data from The Cancer Genome Atlas LUAD cohort were analyzed to identify lactylation cancer subtypes (CSs) using 10 multiomics ensemble clustering techniques. The findings were then validated using the GSE31210 and GSE13213 LUAD cohorts.

A large histological images dataset of gastric cancer with tumour microenvironment annotation for AI.

Gastric cancer (GC) is the third leading cause of cancer death worldwide. Its clinical course varies considerably due to the highly heterogeneous tumour microenvironment (TME). Decomposing the complex TME from histological images into its constituent parts is crucial for evaluating its patterns and enhancing GC therapies.

Pneumocystis Jirovecii Pneumonia in Two Immunosuppressed Non-HIV Infected Patients: A Clinical and Therapeutic Analysis.

Pneumocystis jirovecii pneumonia (PJP) is an opportunistic fungal infection that often occurs secondary to human immunodeficiency virus (HIV) infection. However, for non-HIV immunocompromised patients, such as those undergoing novel immunosuppressive treatments to manage malignancies, organ transplants, or connective tissue diseases, PJP is emerging as an increasing threat. The clinical manifestations of PJP in HIV-infected and non-HIV-infected patients differ significantly.

Phosphor-converted light-emitting diodes in the marine environment: current status and future trends.

The exploitation and utilization of resources in marine environments have ignited a demand for advanced illumination and optical communication technologies. Light-emitting diodes (LEDs), heralded as "green lighting sources", offer a compelling solution to the technical challenges of marine exploration due to their inherent advantages. Among the myriad of LED technologies, phosphor-converted light-emitting diodes (pc-LEDs) have emerged as frontrunners in marine applications.

Disruption of the FOXM1 Regulatory Region Inhibits Tumor Progression in Ovarian Cancer by CRISPR-Cas9.

Ovarian cancer is the seventh most common lethal tumor among women in the world. FOXM1 is a transcription factor implicated in the initiation and progression of ovarian cancer by regulating key oncogenic genes. The role of regulatory regions in regulating the expression of FOXM1 in ovarian cancer is not completely clarified.

Adverse Events of Factor Xa Inhibitors in Pediatric Patients: A Meta-analysis and Pharmacovigilance Study.

Background: This study aimed to provide a comprehensive review of adverse events (AEs) associated with factor Xa (FXa) inhibitors in pediatric patients.

Methods: We searched PubMed, Embase, Cochrane Library, ClinicalTrials.gov, and the European Union Clinical Trials Register for English-language records from the establishment of the database up to October 17, 2023.

Tuning Dual Catalytic Active Sites of Pt Single Atoms Paired with High-Entropy Alloy Nanoparticles for Advanced Li-O Batteries.

To achieve a long cycle life and high-capacity performance for Li-O batteries, it is critical to rationally modulate the formation and decomposition pathway of the discharge product LiO. Herein, we designed a highly efficient catalyst containing dual catalytic active sites of Pt single atoms (Pt) paired with high-entropy alloy (HEA) nanoparticles for oxygen reduction reaction (ORR) in Li-O batteries. HEA is designed with a moderate d-band center to enhance the surface adsorbed LiO intermediate (LiO(ads)), while Pt active sites exhibit weak adsorption energy and promote the soluble LiO pathway (LiO(sol)).

Development of a mitochondrial mini-barcode and its application in metabarcoding for identification of leech in traditional Chinese medicine.

In Traditional Chinese Medicine (TCM), the medicinal leech is vital for treatments to promote blood circulation and eliminate blood stasis. However, the prevalence of counterfeit leech products in the market undermines the quality and efficacy of these remedies. Traditional DNA barcoding techniques, such as the COI barcode, have been limited in their application due to amplification challenges.

Theoretical and Experimental Research on the Short-Range Structure in Gallium Melts Based on the Wulff Cluster Model.

In this paper, the short-range ordering structures of Ga melts has been investigated using the Wulff cluster model (WCM). The structures with a Wulff shape outside and crystal symmetry inside have been derived as the equivalent system to describe the short-range-order (SRO) distribution of the Ga melts. It is observed that the simulated HTXRD patterns of the Ga WCM are in excellent agreement with the experimental data at various temperatures (523 K, 623 K, and 723 K).

Repackable microfluidic molecularly imprinted solid-phase extraction coupled with mass spectrometry (μMISPE-MS) for rapid analysis of mycotoxin in agri-foods: an example of zearalenone.

Mycotoxins are detectable in 60-80% of food crops, posing significant threats to human health and food security, and causing substantial economic losses. Most mitigation approaches focus on detecting mycotoxins with standard methods based on liquid chromatography coupled with mass spectrometry (LC-MS). Typical MS methods require extensive sample preparation and clean-up due to the matrix effect, followed by time-consuming LC separation, complicating the analysis process and limiting analytical throughput.

A large annotated cervical cytology images dataset for AI models to aid cervical cancer screening.

Accurate detection of abnormal cervical cells in cervical cancer screening increases the chances of timely treatment. The vigorous development of deep learning methods has established a new ecosystem for cervical cancer screening, which has been proven to effectively improve efficiency and accuracy of cell detection in many studies. Although many contributing studies have been conducted, limited public datasets and time-consuming collection efforts may hinder the generalization performance of those advanced models and restrict further research.

Pulmonary Hemodynamic Parameters Derived from 4D Flow MR Imaging Can Provide Sensitive Markers for Chronic Obstructive Pulmonary Disease (COPD) Patients with Right Ventricular Dysfunction.

Purpose: To investigate the potential of 4D flow MRI-derived pulmonary hemodynamic parameters as sensitive markers for chronic obstructive pulmonary disease (COPD) patients with right ventricular dysfunction (RVD).

Methods: We enrolled 15 COPD patients combined with RVD and 43 non-RVD participants, all of them underwent pulmonary function tests, thoracic CT and cardiac MR examinations, and the image post-processing analysis was completed. After comparing the 2 groups, the average flow velocity of the main pulmonary artery (Vavg-MPA) and the right pulmonary artery (Vavg-RPA) were identified as statistically significant confounding factors, propensity score matching was used to pair patients controlling for these 2 parameters.

Hijacking endogenous iron to amplify lysosomal-mitochondrial cascade damage for boosting anti-tumor immunotherapy.

The cross-talk between lysosomes and mitochondria is crucial for keeping intracellular homeostasis and metabolic function, providing a promising approach for tumor therapy. Herein, we employed polyvinylpyrrolidone (PVP)-modified Cu-gallic acid (CuGA) complex nano-boosters for amplifying lysosomes-mitochondria cascaded damage, and thereby effectively inducing cuproptosis and pyroptosis of breast tumor cells to boost anti-tumor immunotherapy. The CuGA nano-boosters could hijack lysosomal iron to form a bimetallic catalyst Cu(Fe)GA in situ through ion-exchange reaction, and cause the release of Cu and metal ion dysregulation (i.

Research trends of artificial intelligence and radiomics in lung cancer: a bibliometric analysis.

Background: Extensive research on the application of artificial intelligence (AI) and radiomics in lung cancer has been published in recent years; however, it is necessary to identify the current status, hotspots, and trends in the field. Thus, this study conducted a bibliometric analysis of relevant studies to investigate the application of AI and radiomics in lung cancer.

Methods: Related publications were retrieved from the Web of Science Core Collection (WoSCC).

Social isolation, perceived social support, and type D personality among gastrointestinal cancer survivors in China: A mediating model analysis.

Objective: To explore the mediating effect of social isolation between perceived social support and type D personality in gastrointestinal cancer survivors based on the WHITE heuristic cognitive-behavioral model of emotion cognition theory.

Methods: The study utilized a convenience sampling method to recruit 183 survivors of gastrointestinal cancer who were undergoing chemoradiotherapy. SPSS 26.

The CARE Overdose Response Team in Chicago: A Multidisciplinary Out-of-Hospital Post-Opioid Overdose Intervention.

Objectives: In 2021, the opioid overdose crisis led to 1441 fatalities in Chicago, the highest number ever recorded. Interdisciplinary post-overdose follow-up teams provide care at a critical window to mitigate opioid-related risk and associated fatalities. Our objective was to describe a pilot follow-up program in Chicago including eligible overdose incidents, provision of response team services, and program barriers and successes.

Pure spin currents induced by asymmetric H-passivation in BCP nanoribbons.

Inspired by the recently reported novel two-dimensional material BCP, we performed one-dimensional shearing along the zigzag direction to obtain four BCP nanoribbons with various edge atom combinations. An asymmetric hydrogen passivation scheme was employed to modulate the electronic properties and successfully open the band gap, especially the 2H-1H passivation with dihydrogenation and monohydrogenation at the top and bottom edges, respectively, achieving bipolar magnetic semiconductors with edge P-atoms contributing to the main magnetism. Furthermore, three crucial spin-polarized transmission spectra yielded a significant spin-dependent Seebeck effect (SDSE), displaying superior thermoelectric conversion capabilities by generating pure spin currents.

Revealing the Overlooked Catalytic Ability of γ-AlO: Efficient Activation of Peroxymonosulfate for Enhanced Water Treatment.

Activated alumina (γ-AlO) is one of the few nanomaterials manufactured at a ton-scale and successfully implemented in large-scale water treatment. Yet its role in advanced oxidation processes (AOPs) has primarily been limited to functioning as an inert carrier due to its inherently nonredox nature. This study, for the first time, presents the highly efficient capability of γ-AlO to activate peroxymonosulfate (PMS) for selectively eliminating electron-rich organic pollutants in the presence of Cl.

Association of Preoperative Nutritional Status with Sarcopenia in Patients with Gastrointestinal Malignancies Assessed by Global Leadership Initiative in Malnutrition Criteria: A Prospective Cohort Study.

Introduction: The Global Leadership Initiative in Malnutrition (GLIM) consensus highlights the importance of using the GLIM criteria as a standardized approach to diagnosing malnutrition, particularly in patients with cachexia. Although many existing studies have utilized the GLIM criteria to assess the association between malnutrition and malignant tumor patients, there remains relatively little research exploring the specific relationship between malnutrition and sarcopenia. This study aimed to investigate the correlation between malnutrition under the GLIM criteria and preoperative sarcopenia in patients with gastrointestinal malignancies.

Soft X-ray tomography analysis of mitochondria dynamics in Saccharomyces cerevisiae.

Background: Mitochondria are highly dynamic organelles that constantly undergo processes of fission and fusion. The changes in mitochondrial dynamics shape the organellar morphology and influence cellular activity regulation. Soft X-ray tomography (SXT) allows for three-dimensional imaging of cellular structures while they remain in their natural, hydrated state, which omits the need for cell fixation and sectioning.

Molecular Mechanism: Inhibition of T-2 Toxin Synthesis by Surfactin in Dried Fish: Induction of Nucleation by ROS Accumulation.

(1) T-2 toxin synthesized by () can cause deterioration of dried fish and endanger human health. (2) The molecular mechanism by which antibacterial lipopeptides surfactin inhibited growth and toxin production was elucidated by investigating the intracellular ROS production pathway and the subcellular distribution and transcriptional activity of the transcription factor and its regulation of gene in . (3) Surfactin caused hyphal damage and nucleic acid and protein leakage; thus, the growth of was disrupted.

SCOUT: Skull-Corrected Optimization for Ultrasound Transducers.

Transcranial focused ultrasound has been studied for non-invasive and localized treatment of many brain diseases. The biggest challenge for focusing ultrasound onto the brain is the skull, which attenuates ultrasound and changes its propagation direction, leading to pressure drop, focus shift, and defocusing. We presented an optimization algorithm which automatically found the optimal location for placing a single-element focused transducer.

Unexpected chloride-triggered organics removal in the zirconium oxide activated peroxymonosulfate system.

Chloride ion (Cl) is ubiquitous in diverse water bodies, yet poses a longstanding challenge in water pollution control by hindering the efficiency of pollutant degradation. Herein, we proposed a novel concept involving the direct utilization of endogenous Cl ions in water for rapid water purification within a non-redox zirconium oxide (ZrO)-activated peroxymonosulfate (PMS) system. In this process, PMS was complexed on the ZrO surface through inner-sphere coordination, and effectively activated by the partial electron cloud deviation from Zr(IV) sites to PMS, thereby forming a metastable surface complex with an elevated redox potential.