Preparation and antioxidant properties of tannic acid/copper ion nanozyme hybrid nanofibrous membranes.

Excess free radicals can have some negative effects on human health. In this paper, a nanozyme was successfully constructed by the coordination of copper ions and tannic acid, and its structure and elemental distribution were determined by Fourier transform infrared spectroscopy, scanning electron microscopy and X-ray photoelectron spectroscopy. Free radical scavenging experiments confirmed that it possessed superoxide dismutase-like activity, catalase-like activity, and hydroxyl radical scavenging ability.

Bright Nanocomposites based on Quantum Dot-Initiated Photocatalysis.

Integrating quantum dots (QDs) into polymer matrix to form nanocomposites without compromising the QD photoluminescence (PL) is crucial to emerging QD light-emitting and solar energy conversion fields. However, the most widely-used bulk polymerization technique, where monomers serve as the QD solvent, usually leads to QD PL quenching caused by radical initiators. Here we demonstrate high-brightness nanocomposites with near-unity PL quantum yield (QY), through a novel QDs-catalyzed (-initiated) bulk polymerization without using any radical initiators.

Letrozole-Based Near-Infrared Dynamic Imaging Targeting Ductal-Vascular RhoJ From Pancreatic Intraepithelial Neoplasia to Pancreatic Ductal Adenocarcinoma.

Pancreatic ductal adenocarcinoma (PDAC) relies heavily on neoangiogenesis for its progression, making early detection crucial. Here, LTZi-MHI148 (Letrozole inhibitor bonding with MHI-148 dye), a near-infrared (NIR) fluorescent agent is developed, to target RhoJ (Ras Homolog Family Member J), a protein expressed in neonatal vasculature, for both imaging and therapy of early PDAC. This agent is synthesized by conjugating Letrozole with MHI-148, exhibiting excellent NIR characteristics and photostability.

CA IX-targeted AgS quantum dots bioprobe for NIR-II imaging-guided hypoxia tumor chemo-photothermal therapy.

Hypoxia is the common characteristic of almost all solid tumors, which prevents therapeutic drugs from reaching the tumors. Therefore, the development of new targeted agents for the accurate diagnosis of hypoxia tumors is widely concerned. As carbonic anhydrase IX (CA IX) is abundantly distributed on the hypoxia tumor cells, it is considered as a potential tumor biomarker.

Etched stainless steel wire modified with conjugated microporous polymers-F6 for jacket-free stir bar sorptive extraction of benzoylureas in juice sample.

Benzoylurea (BU) insecticides have been widely used for pest control as third-generation insecticides. Considering that their residues in food may cause adverse effects on human health, the upper limits of BUs remaining in food have been set by the administration. Therefore, it is essential to develop a sensitive and efficient analytical method to determine the residues of BUs in food.

A near-infrared light-promoted self-healing photothermally conductive polycarbonate elastomer based on Prussian blue and liquid metal for sensors.

Composite elastomers with elasticity, conductivity, and self-healing properties have gained tremendous interest due to the imperative demands in the fields of stretchable electronics and soft robotics. However, the self-healing performance and the amount of filler are contradictory. Herein, a new conductive self-healing composite elastomer is developed by uniformly dispersing EGaIn droplets and Prussian blue nanoparticles (PBNPs) in a bran-new elastomer which cross-linked the linear polymer that obtained by ring-opening polymerization of trimethylene carbonate and 5-methyl-5-carboxytrimethylene carbonate initiated by polyethylene glycol by aluminum chloride.

First principles insights into the interaction mechanism of iron doped thermally activated kaolinite with Cd and Pb pollutants in organic solid waste incineration flue gas.

Incineration of organic solid wastes is accompanied by the heavy metal emission through flue gas. As an inexpensive and efficient heavy metal adsorbent, the improvement of kaolinite adsorption performance for heavy metals has drawn widespread interests. In this work, the interaction mechanisms between various kaolinite surfaces and Cd/Pb species are explored through first principles calculations.

Albumin-Based Cyanine Crizotinib Conjugate Nanoparticles for NIR-II Imaging-Guided Synergistic Chemophototherapy.

Colorectal cancer (CRC) is presently the third deadliest cancer in the world. This malignant cancer usually precedes the progression of precancerous lesions, and it is challenging to distinguish its nuanced morphological changes. Molecular-based near-infrared-II (NIR-II) fluorescence imaging can effectively recognize lesion targets to improve image contrast and increase early tumor detection compared with traditional wide-light screening endoscopy.

Novel Structural Design and Adsorption/Insertion Coordinating Quasi-Metallic Na Storage Mechanism toward High-performance Hard Carbon Anode Derived from Carboxymethyl Cellulose.

Hard Carbon have become the most promising anode candidates for sodium-ion batteries, but the poor rate performance and cycle life remain key issues. In this work, N-doped hard carbon with abundant defects and expanded interlayer spacing is constructed by using carboxymethyl cellulose sodium as precursor with the assistance of graphitic carbon nitride. The formation of N-doped nanosheet structure is realized by the CN• or CC• radicals generated through the conversion of nitrile intermediates in the pyrolysis process.

CDK12 and Integrator-PP2A complex modulates LEO1 phosphorylation for processive transcription elongation.

Cyclin-dependent kinase 12 (CDK12) interacts with cyclin K to form a functional nuclear kinase that promotes processive transcription elongation through phosphorylation of the C-terminal domain of RNA polymerase II (Pol II). To gain a comprehensive understanding of CDK12's cellular function, we used chemical genetic and phosphoproteomic screening to identify a landscape of nuclear human CDK12 substrates, including regulators of transcription, chromatin organization, and RNA splicing. We further validated LEO1, a subunit of the polymerase-associated factor 1 complex (PAF1C), as a bona fide cellular substrate of CDK12.

Construction of nano-drug delivery and antitumor system of stimuli-responsive polypeptides.

The size of the nanoparticles is moderate and the dispersion is well, which will not be recognized nonspecifically and clearance by the endothelial reticular system. In this study, stimuli-responsive polypeptides nano-delivery system has been constructed, which can realize the response to various stimuli in the tumor microenvironment. Tertiary amine groups are grafted to the side chain of polypeptides as the point of charge reversal and particle expansion.

Sustained-release behavior and the antitumor effect of charge-convertible poly(amino acid)s drug-loaded nanoparticles.

Enhancing tissue permeability and achieving drug aggregation is the key to targeted tumor therapy. A series triblock copolymers of poly(ethylene glycol)-poly(L-lysine)-poly(L-glutamine) were synthesized by ring-opening polymerization, and charge-convertible nano-delivery system was constructed by loading doxorubicin (DOX) with 2-(hexaethylimide) ethanol on side chain. In normal environment (pH = 7.

Construction of poly(amino acid)s nano-delivery system and sustained release with redox-responsive.

A series of novel poly(amino acid)s materials were designed to prepare drug-loaded nanoparticles by physical encapsulation and chemical bonding. The side chain of the polymer contains a large number of amino groups, which effectively increases the loading rate of doxorubicin (DOX). The structure contains disulfide bonds that showing a strong response to the redox environment, which can achieve targeted drug release in the tumor microenvironment.

Boron-Catalyzed Graphitization Carbon Layer Enabling LiMn Fe PO Cathode Superior Kinetics and Li-Storage Properties.

The poor electrode kinetics and low conductivity of the LiMn Fe PO cathode seriously impede its practical application. Here, an effective strategy of boron-catalyzed graphitization carbon coating layer is proposed to stabilize the nanostructure and improve the kinetic properties and Li-storage capability of LiMn Fe PO nanocrystals for rechargeable lithium-ion batteries. The graphite-like BC is derived from B-catalyzed graphitization coating layers, which can not only effectively maintain the dynamic stability of the LiMn Fe PO nanostructure during cycling, but also plays an important role in enhancing the conductivity and Li migration kinetics of LiMn Fe PO @B-C.

Highly effective removal of Hg(ii) solution using corn bract@MoS as a new biomass adsorbent.

As known, mercury contamination is one of the current environmental issues due to the high toxicity of mercury. Corn bract (CB) is an agricultural by-product, and its final treatment is generally incineration that causes air pollution. In this study, a new type of high-efficiency biomass adsorbent (CB@MoS) for adsorption of Hg(ii) was obtained, and its morphology and structure were characterized with FT-IR, XRD, SEM and TEM.

A comprehensive review of the heavy metal issues regarding commercial vanadium‑titanium-based SCR catalyst.

Facing the increasing demand of atmosphere pollutant control, selective catalytic reduction (SCR) technology has been widely applied in various industries for NO abatement. However, in the condition of complicated flue gas components, the heavy metal issue is a great challenge to the catalyst deactivation and atmospheric pollution control. In this review, with the comprehensive consideration of SCR catalysts in heavy metal-rich flue gas scenarios, the distribution character of heavy metals in SCR system is firstly summarized, then the detailed interaction mechanism between heavy metals and the vanadium‑titanium-based catalyst is discussed.

Determination of water in organic solvents and raw food products by fluorescence quenching of a crystalline vinyl-functionalized COF.

Covalent organic frameworks (COFs) with good chemical stability, flexible chemical functionalization, tunable pore sizes, and high specific surface areas have been increasingly employed in the field of fluorescence sensing. In this work, a crystalline vinyl-functionalized COF TzDa-V was facilely prepared through a room-temperature synthetic method via condensation reaction between 4,4',4″-(1,3,5-triazine-2,4,6-triyl)trianiline (Tz) and 2,5-diallyloxyterephthalaldehyde (Da-V). The intermolecular charge transfer (ICT) effect endowed the TzDa-V with fluorescence characteristic, and it was sensitive to trace water and can be quenched due to the disruption of ICT process by water.

Emergency Response Resource Allocation in Sparse Network Using Improved Particle Swarm Optimization.

Western China is a sparsely populated area with dispersed transportation infrastructure, making it challenging to meet people's accessibility and mobility requirements. Rescue efficiency in sparse networks is severely hampered by the difficulty rescue teams have in getting to the scene of abrupt traffic accidents. This paper develops a layout optimization model for multiple rescue points to address this issue, suggests an improved particle swarm algorithm by including a variation that can reduce optimization time and avoid the disadvantage of precocity, and designs a MATLAB program using an adaptive variation algorithm.

Synthesis of multifunctional crown ether covalent organic nanospheres as stationary phase for capillary electrochromatography.

Crown ethers are macrocyclic polyether compounds containing multiple -oxo-methylene-structural units, which are often used for recognition of metal ions and ammonium ions. Inspired by the molecular design of rotaxanes, a novel covalent organic nanospheres material (CON ADBC-Tp) constructed by 4,4'-diaminodibenzo-18-crown-6 (ADBC) and 2,4,6-triformylphloroglucinol (Tp) was rationally designed as stationary phase for the separation of compounds containing imidazole structure. Scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FT-IR) were carried out to confirm the morphology and composition of ADBC-Tp and ADBC-Tp modified capillary column.

Synergistic Effect, Structural and Morphology Evolution, and Doping Mechanism of Spherical Br-Doped Na V (PO ) F /C toward Enhanced Sodium Storage.

Na V (PO ) F has attracted wide attention due to its high voltage platform, and stable crystal structure. However, its application is limited by the low electronic conductivity and the ease formation of impurity. In this paper, the spherical Br-doped Na V (PO ) F /C is successfully obtained by a one-step spray drying technology.

Green and Moderate Activation of Coal Fly Ash and Its Application in Selective Catalytic Reduction of NO with NH.

Coal fly ash (CFA) is an ideal source for the preparation of heterogeneous catalysts due to its abundant silicon and aluminum oxides, but its activity needs to be improved. In this study, a green and moderate approach for CFA activation was proposed, and a series of CFA-based catalysts were prepared for NO selective catalytic reduction (SCR). The results indicated that CFA could be well activated via mechanochemical activation with 3 h of milling duration in 1 mol/L of acetic acid, and 90% of NO removal was achieved over the CFA-based catalyst in 250 to 375 °C.

Insights into the sodium storage mechanism of BiTe nanosheets as superior anodes for sodium-ion batteries.

Although bismuth-based anode materials for sodium-ion batteries (SIBs) have attracted wide attention, their large volume variation hinders their actual applications, especially in BiTe systems. In this study, BiTe nanosheets (BT-Ns) are fabricated by a novel strategy a solvent reductive reaction. The elements Bi and Te are spontaneously grown into ultrathin nanosheets because the hexagonal crystal of BiTe has a strong tendency to grow horizontally.

Facile synthesis of novel multifunctional β-cyclodextrin microporous organic network and application in efficient removal of bisphenol A from water.

Here, a novel multifunctional β-cyclodextrin microporous organic network (CD-MON) has been successfully synthesized and used to remove bisphenol A (BPA) from water. The morphology and composition of the synthesized CD-MON were confirmed. The combination of hydrophobic interaction, π-π interaction inclusion mechanism and hydrogen bonding endowed CD-MON to exhibit superior adsorption capacity toward BPA.

Water Effects on Colloidal Semiconductor Nanocrystals: Correlation of Photophysics and Photochemistry.

With high-quality CdSe/CdS core/shell nanocrystals as the main model system and under a controlled atmosphere, responses of photoexcited semiconductor nanocrystals to two active species (water and/or oxygen) in an ambient environment are studied systematically. Under photoexcitation, although high-quality semiconductor nanocrystals in either thin solid films or various solutions have a near-unity photoluminescence quantum yield, there is still a small probability (∼10 per photon absorbed) to be photoreduced by the water molecules efficiently accumulated in the highly hydrophilic nanocrystal-ligands interface. The resulting negatively charged nanocrystals are the starting point of most photophysical variations, and the hydroxyl radical─key photo-oxidation product of water─plays the main role for initiating various photochemical processes.

Intrinsic mechanism insight of the interaction between lead species and the Vanadium-based catalysts based on First-principles investigation.

Lead (Pb) species trigger serious poisoning of selective catalytic reduction (SCR) catalysts. To improve the Pb resistance ability, revealing the impact mechanism of Pb species on the commercial SCR catalysts from a molecular level is of great significance. Herein, first-principles calculations were applied to unveil the Pb adsorption mechanism on the vanadium-based catalysts, the results were also compared with the previous experimental findings.