Effect of Thermal Reflow on Microstructural Morphology and Contact Mechanics in the Photo-Lithographic Fabrication of Biomimetic Adhesive Materials.

Bionic adhesive materials with 3D complex micro/nanostructures have several advantages of low preload, strong adhesion, switchable adhesion, etc. As the primary high-precision fabrication method for such materials, lithography is inherently limited by its 2D processing capabilities. Achieving complex 3D morphologies typically requires auxiliary processes, such as dipping and double-sided separate UV exposures, which increase both the complexity and limitations of the fabrication process.

Improving Corrosion Resistance of Zircaloy-4 via High-Current Pulsed Electron Beam Surface Irradiation.

Zircaloy-4 is extensively used in nuclear reactors as fuel element cladding and core structural material. However, the safety concerns post-Fukushima underscore the need for further enhancing its high-temperature and high-pressure water-side corrosion resistance. Therefore, this study aimed to investigate the effects of high-current pulsed electron beam (HCPEB) irradiation on the microstructures and corrosion resistance of Zircaloy-4, with the goal of improving its performance in nuclear applications.

Accumulation of microtubule-associated protein tau promotes hepatocellular carcinogenesis through inhibiting autophagosome-lysosome fusion.

Dysregulated expression of microtubule-associated protein tau (MAPT) has been reported in a variety of human cancers. However, whether and how Tau influences hepatocellular carcinogenesis remains elusive. This study was aimed to investigate the role and the underlying mechanism of Tau in the proliferation, invasion, migration and sorafenib sensitivity of hepatocellular carcinoma (HCC) cells.

Two novel triazine-based quaternary ammonium salt Gemini surfactants as potential corrosion inhibitors for carbon steel in a sulfate-reducing bacteria solution: Experimental and theoretical studies.

In this paper, two triazine ring-containing quaternary ammonium salt Gemini surfactants (C-2-C and C-2-C) were synthesized. The minimum inhibitory concentrations against sulfate-reducing bacteria (SRB) of C-2-C, C-2-C and dodecyl dimethyl benzyl ammonium chloride (1227) were determined using the double-dilution method. The performance of C-2-C and C-2-C in inhibiting carbon steel corrosion in the presence of SRB was examined, with 1227 serving as a control sample.

Multi-Mechanism Collaborative Bionic Fixation Technique Between a Wide Range of Solid Interfaces.

For rough surfaces, stable, fast, and repeatable fixation has wide applicability in transportation, fire protection, and other fields. Different rough surfaces present technical challenges for achieving convenient and reliable fixation. Based on the highly adhesive attachment structures of typical organisms, a multi-mechanism (negative pressure adsorption, mechanical locking, and chemical bonding) cooperative bionic fixation device is proposed.

Fermented Palm Kernel Cake Improves the Rumen Microbiota and Metabolome of Beef Cattle.

In this study, we utilised palm kernel cake as a substrate and fermented it with a composite of bacteria ( CGMCC No. 27203 and CGMCC No. 27202) and enzymes.

Correlation between hyperlipidemia and serum vitamin D levels in an adult Chinese cohort.

Vitamin D deficiency has emerged as a significant concern in public health due to its potential association with various metabolic disorders. This study aimed to investigate the relationship between serum vitamin D levels and the susceptibility to hyperlipidemia among adults. Using a multi-stage sampling approach, we recruited a cohort of 2072 eligible individuals aged over 18 years.

Analysis of differences in the rumen microbiome and metabolic function in prepartum dairy cows with different body condition scores.

Background: The rumen is a crucial digestive organ for dairy cows. The rumen microbiota assists in the digestion of plant feed through microbe-mediated fermentation, during which the plant feed is transformed into nutrients for the cow's use. Variations in the composition and function of the rumen microbiome affect the energy utilization efficiency of dairy cows, which is one of the reasons for the varying body condition scores (BCSs).

Magnetic Array-Aided Visualizing PEMFC Degradation Heterogeneity.

Analyzing degradation heterogeneity of proton exchange membrane fuel cell (PEMFC) while maintaining high practicality is consistently challenging, primarily due to the destructive and costly nature of existing techniques relying on material characterization. In this work, a designed magnetic array integrating 16 sensors within 25 cm space is used for direct scanning and imaging of PEMFC performance heterogeneity during its degradation. Results are validated through degradation mechanism analysis and material characterization, confirming its potential in guiding the development of durable materials.

Propensity matched post-transplant survival in durable CF-axial pump BTT patients with and without diabetes: A UNOS database analysis.

Diabetes and post-transplant survival have been linked. However, the impact on post-transplant survival of patients supported on Continuous Flow (CF) axial left ventricular assist devices (LVAD) as a bridge to transplant (BTT) with diabetes has not been widely studied. This study attempts to assess the impact of diabetes type II (DM type II) as a comorbidity influencing survival patterns in the post-cardiac transplant population supported on LVADs and to test if the presence of a pre- transplant durable LVAD acts as an independent risk factor in long-term post-transplant survival.

Antitumor Effect of Apcin on Endometrial Carcinoma via p21-Mediated Cell Cycle Arrest and Apoptosis.

Objective: Endometrial carcinoma (EC) is a prevalent gynecological malignancy characterized by increasing incidence and mortality rates. This underscores the critical need for novel therapeutic targets. One such potential target is cell division cycle 20 (CDC20), which has been implicated in oncogenesis.

Purple sweet potato anthocyanins normalize the blood glucose concentration and restore the gut microbiota in mice with type 2 diabetes mellitus.

Background: This study investigated the effects of purple sweet potato anthocyanins (PSPA) in a type 2 diabetes mellitus (T2DM) mouse model.

Methods: Sixty-five male mice were randomly divided into one control group and four experimental groups, which were fed with a high-fat diet and intraperitoneally injected with streptozotocin (STZ) to induce T2DM. The model mice were treated with 0 (M), 227.

CYP2E1 deficit mediates cholic acid-induced malignant growth in hepatocellular carcinoma cells.

Background: Increased level of serum cholic acid (CA) is often accompanied with decreased CYP2E1 expression in hepatocellular carcinoma (HCC) patients. However, the roles of CA and CYP2E1 in hepatocarcinogenesis have not been elucidated. This study aimed to investigate the roles and the underlying mechanisms of CYP2E1 and CA in HCC cell growth.

General anesthetic agents induce neurotoxicity through oligodendrocytes in the developing brain.

General anesthetic agents can impact brain function through interactions with neurons and their effects on glial cells. Oligodendrocytes perform essential roles in the central nervous system, including myelin sheath formation, axonal metabolism, and neuroplasticity regulation. They are particularly vulnerable to the effects of general anesthetic agents resulting in impaired proliferation, differentiation, and apoptosis.

Physicochemical, structural and functional properties of low methoxyl pectin‑iron (III) complex and its effect on rats with iron deficiency anemia.

Iron deficiency anemia (IDA) is the most common nutritional disease worldwide. In this study, a low methoxyl pectin (LMP)‑iron(III) complex was prepared. The physicochemical and structural properties were characterized by HPSEC, HPIC, CV, FTIR, H NMR, XRD, SEM and CD.

Effects of Individual Essential Amino Acids on Growth Rates of Young Rats Fed a Low-Protein Diet.

To investigate the effects of individual essential amino acids (EAA) on growth and the underlying mechanisms, EAA individually supplemented a low-protein (LP) diet fed to young rats in the present study. Treatments were an LP diet that contained 6% crude protein (CP), a high-protein (HP) diet that contained 18% CP, and 10 LP diets supplemented with individual EAA to achieve an EAA supply equal to that of the HP diet. The CP concentration of the LP diet was ascertained from the results of the first experiment, which examined the effects of dietary CP concentrations on growth rates, with CP ranging from 2% to 26%.

Long-term exposure to 6-PPD quinone at environmentally relevant concentrations causes neurotoxicity by affecting dopaminergic, serotonergic, glutamatergic, and GABAergic neuronal systems in Caenorhabditis elegans.

6-PPD quinone (6-PPDQ), an emerging environmental pollutant, is converted based on 6-PPD via ozonation. However, a systematic evaluation on possible neurotoxicity of long-term and low-dose 6-PPDQ exposure and the underlying mechanism remain unknown. In the present work, 0.