Mechanism Study on the Immobilization of Cu/Pb in Aqueous Phase by Mineral Co-Milling-Modified Biochar.

A large number of studies have shown that the modification of biochar can greatly improve its adsorption capacity. This study adopts a one-step ball milling technology without solvent medium, using sawdust biochar (600 °C) and attapulgite/diatomaceous earth to prepare MABC10%/MDBC10% (mass ratio: 10% attapulgite/diatomite +90% biochar coabrasive). Characterization experiments show that attapulgite/diatomite was successfully loaded on biochar and has more C/O functional groups and wider adsorption pore sizes.

Incrementally Adapting Pretrained Model Using Network Prior for Multi-Focus Image Fusion.

Multi-focus image fusion can fuse the clear parts of two or more source images captured at the same scene with different focal lengths into an all-in-focus image. On the one hand, previous supervised learning-based multi-focus image fusion methods relying on synthetic datasets have a clear distribution shift with real scenarios. On the other hand, unsupervised learning-based multi-focus image fusion methods can well adapt to the observed images but lack the general knowledge of defocus blur that can be learned from paired data.

Sustained free chlorine-releasing polydimethylsiloxane/Ca(ClO) materials with long-lasting disinfection efficacy.

A novel sustained chlorine-releasing polydimethylsiloxane/Ca(ClO) (PDMS/Ca(ClO)) material was fabricated by encapsulating Ca(ClO) in a PDMS matrix due to its high hydrophobicity and high chemical stability, which showed immediate-responsive and long-lasting antibacterial capabilities in aqueous conditions. Free chlorine could be released from the PDMS/Ca(ClO) after immersion in water for 2 min and could also be sustainedly released for 2 weeks, while the released concentration is negatively related to the duration time and positively with the initial Ca(ClO) contents. Additionally, Ca(ClO) powder as a filler significantly affects the crosslinking and pore size of PDMS.

Carnitine functions as an enhancer of NRF2 to inhibit osteoclastogenesis via regulating macrophage polarization in osteoporosis.

Osteoporosis, which manifests as reduced bone mass and deteriorated bone quality, is common in the elderly population. It is characterized by persistent elevation of macrophage-associated inflammation and active osteoclast bone resorption. Currently, the roles of intracellular metabolism in regulating these processes remain unclear.

pH-responsive on-demand release of eugenol from metal-organic frameworks for synergistic bacterial killing.

Bacterial infections are a big challenge in clinical treatment, making it urgent to develop innovative antibacterial systems and therapies to combat bacterial infections. In this study, we developed a novel MOF-based synergistic antibacterial system (Eu@B-UiO-66/Zn) by loading a natural antibacterial substance (eugenol) with hierarchically porous MOF B-UiO-66 as a carrier and further complexing it with divalent zinc ions. Results indicate that the system achieved a controlled release of eugenol under pH responsive stimulation, with the complexation ability of eugenol and Zn ions as a switch.

Nitisinone attenuates cartilage degeneration and subchondral osteoclastogenesis in osteoarthritis and concomitantly inhibits the cGAS/STING/NF-κB pathway.

Osteoarthritis (OA) is a chronic degenerative joint disease characterized by cartilage degeneration and subchondral bone remodelling. Currently, conservative treatment strategies cannot effectively alleviate the progression of OA. In this study, we used computer network analysis to show that Nitisinone (NTBC) is closely related to extracellular matrix degradation in OA and mainly interferes with the TNF-α signaling pathway.

Selective recycling of lithium from spent LiNiCoMnO cathode via constructing a synergistic leaching environment.

The global response to lithium scarcity is overstretched, and it is imperative to explore a green process to sustainably and selectively recover lithium from spent lithium-ion battery (LIB) cathodes. This work investigates the distinct leaching behaviors between lithium and transition metals in pure formic acid and the auxiliary effect of acetic acid as a solvent in the leaching reaction. A formic acid-acetic acid (FA-AA) synergistic system was constructed to selectively recycle 96.

Macrophage migration inhibitory factor (MIF) promotes intervertebral disc degeneration through the NF-κB pathway, and the MIF inhibitor CPSI-1306 alleviates intervertebral disc degeneration in a mouse model.

Lumbar intervertebral disc degeneration(IDD) is a prevalent inflammatory disease caused by many proinflammatory factors, such as TNF and IL-1β. Migration inhibitory factor (MIF) is an upstream inflammatory factor widely expressed in vivo that is associated with a variety of inflammatory diseases or malignant tumors and has potential therapeutic value in many diseases. We explored the role of MIF in intervertebral disc degeneration by regulating the content of exogenous MIF or the expression of MIF in cells.

Preparation of amino-modified carbon quantum dots-ZnO/cellulose nanofiber multifunctional hydrogel: Enhanced adsorption synergistic photoreduction and reversible fluorescence response visual recognition of Cr(VI).

This work innovatively used cellulose nanofibers as a photocatalyst carrier, which could recycle nano-photocatalysts and minimize nanoparticle aggregation. The morphology, structures, chemical composition, optical-electronic properties and photocatalytic performance of amino-modified carbon quantum dots-ZnO/cellulose nanofiber (N-CQDs-ZnO/CNF: ZCH-2) hydrogel were characterized by SEM, TEM, BET, EDS, XRD, FTIR, UV-vis, XPS, PL and other techniques. The mechanism of Cr(VI) adsorption synergistic photoreduction by ZCH-2 was discussed in detail.

Assessing the probiotic potential, antioxidant, and antibacterial activities of oat and soy milk fermented with strains isolated from Tibetan Kefir.

Sufficient intake of probiotics has been shown to help in the digestion, protect the body against pathogenic microorganisms and boost the immune system. Recently, due to high prevalence of milk allergies and lactose intolerance in population, the non-dairy based probiotic alternative are becoming increasing popular. In this context, the oat milk and soya milk-based fermented products can be an ideal alternative for the development of Lactic acid bacteria bacteria based probiotics.

Advances in Hydrogel Adhesives for Gastrointestinal Wound Closure and Repair.

Millions of individuals undergo gastrointestinal (GI) tract surgeries each year with common postoperative complications including bleeding, perforation, anastomotic leakage, and infection. Today, techniques such as suturing and stapling seal internal wounds, and electrocoagulation stops bleeding. These methods induce secondary damage to the tissue and can be technically difficult to perform depending on the wound site location.

Rapid extraction of valuable metals from spent LiNiCoMnO cathodes based on synergistic effects between organic acids.

The slow rate of organic acid leaching is the main factor hindering the ecological recycling of spent lithium-ion battery (LIB) cathode materials. Here, a mixed green reagent system of ascorbic acid and acetic acid is proposed to leach valuable metal ions from the spent LIBs cathode materials rapidly. In 10 min, 94.

Formononetin improves the inflammatory response and bone destruction in knee joint lesions by regulating the NF-kB and MAPK signaling pathways.

Formononetin (FMN) is a phytoestrogen that belongs to the isoflavone family. It has antioxidant and anti-inflammatory effects, as well as, many other biological activities. Existing evidence has aroused interest in its ability to protect against osteoarthritis (OA) and promote bone remodeling.

Ag/AgO with NIR-Triggered Antibacterial Activities: Photocatalytic Sterilization Enhanced by Low-Temperature Photothermal Effect.

Purpose: A synergistic antibacterial system employing photocatalytic performance and low-temperature photothermal effect (LT-PTT) with the potential for infectious skin wound healing promotion was developed.

Methods: Ag/AgO was synthesized with a two-step method, and its physicochemical properties were characterized. After its photocatalytic performance and photothermal effect were evaluated under 0.

Near-Infrared-Enhanced Dual Enzyme-Mimicking Ag-TiO@Alginate Microspheres with Antibactericidal and Oxygeneration Abilities to Treat Periodontitis.

The effective treatment for periodontitis is to completely and sustainedly eradicate the bacterial pathogens from the complex periodontal pockets. Local sustained-release antibiotics as a complementary treatment after scaling and root planning can sustainedly combat bacterial pathogens in the periodontal pockets to help treat the disease, but the increasing concern of bacterial resistance limits its future use. Here, we reported a local antibacterial system based on microsized multifunctional Ag-TiO encapsulated in alginate (ATA) microspheres.

MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP1.

Bone metabolic homeostasis is largely dependent on the dynamic balance between osteoblasts and osteoclasts. MicroRNAs (miRNAs) play critical roles in regulating bone metabolism. In this study, we explored the role of a new miRNA (miR-148a) in osteoporosis.

Constructing mesoporous Zr-doped SiO onto efficient Z-scheme TiO/g-CN heterojunction for antibiotic degradation via adsorption-photocatalysis and mechanism insight.

Novel modified-TiO/Zr-doped SiO/g-CN ternary composite is fabricated via an in-situ grow of porous Zr-SiO layer to TiO/g-CN heterojunction, which exhibits well adsorption-photocatalytic performance under simulated solar light irradiation. The nano-size mesoporous TiO are dispersed on the lamellar g-CN, and the Zr-SiO is in-situ fabricated onto the surface of g-CN sheets. The adsorption occurs on the SiO layers, and doping Zr element to SiO enhances the adsorption of pollutants, while the photocatalytic reaction occurs on the valence band (VB) of TiO and conduction band (CB) of g-CN, which gives reactive oxygen species of ∙O, h, and ∙OH for high efficient decomposition of antibiotics, i.

Correction: Xie et al. Synergistic Effect of MoS and SiO Nanoparticles as Lubricant Additives for Magnesium Alloy-Steel Contacts. 2017, , 154.

In the original publication [...

Anatase quantum dots decorated silica/carbon lamellas for removal of antipsychotic drugs via adsorption-photocatalysis and toxicity evaluation.

In this work, discrete quantum dots of crystallized anatase TiO are successfully anchored on carbon nanosheets containing amorphous SiO via templated self-assembly and pyrolysis routes. The novel hybrid photocatalyst of TiO/C/SiO exhibits well coupled adsorption and visible light photocatalysis on chlorpromazine (CPZ) and the rate constants are 0.0223 and 0.

Dental follicle cells-derived small extracellular vesicles inhibit pathogenicity of Porphyromonas gingivalis.

Objective: It aims to explore the effect of dental follicle cells-derived small extracellular vesicles (D-sEVs) with or without lipopolysaccharides (LPS) pretreating on the pathogenicity of Porphyromonas gingivalis (P. gingivalis).

Methods: The antibacterial effects of D-sEV were evaluated by measuring the growth, biofilm formation, gingipains, and type IX secretion system (T9SS) expression of P.

Gelatin methacryloyl-alginate core-shell microcapsules as efficient delivery platforms for prevascularized microtissues in endodontic regeneration.

Combined injectable cell-laden microspheres and angiogenesis approaches are promising for functional vascularized endodontic regeneration. However, advanced microsphere designs and production techniques that benefit practical applications are rarely developed. Herein, gelatin methacryloyl (GelMA)-alginate core-shell microcapsules were fabricated to co-encapsulate human dental pulp stem cells (hDPSCs) and human umbilical vein endothelial cells (HUVECs) based on a coaxial electrostatic microdroplet technique.

Perfluorinated conjugated microporous polymer for targeted capture of Ag(I) from contaminated water.

The maximum targeted capture silver from contaminated water is urgently necessary for sustainable development. Herein, the perfluorination conjugated microporous polymer adsorbent (F-CMP) has been fabricated by Sonogashira-Hagihara coupling reaction and employed to remove Ag(I) ions. Characterizations of NMR, XPS and FT-IR indicate the successful synthesis of F-CMP adsorbent.

Critical strategies for recycling process of graphite from spent lithium-ion batteries: A review.

With the explosive growth of spent lithium-ion batteries (LIBs), the effective recycling of graphite as a key negative electrode material has become economically attractive and environmentally significant. This review reports the recent research progress in recycling strategies for spent graphite from the perspectives of separation and reuse. First, technologies for separating graphite powder after direct crushing and artificially splitting are introduced, and the shortcomings of cost control and separation efficiency are reported.

Synchronous Construction of the Hierarchical Pores and High Hydrophobicity of Stable Metal-Organic Frameworks through a Dual Coordination-Competitive Strategy.

Hierarchical-pore construction and functionalities are critical to further extend the applications of some stable MOFs, such as water remediation, fuel purification, oil/water separation, and self-cleaning, which are rarely achieved simultaneously. Herein, we demonstrate a method of synchronously constructing high-hydrophobicity Zr-based metal-organic frameworks with hierarchical pores (HP-UiO-66) through a dual coordination-competitive strategy. The addition of alkanoic acids and Zn ions as coordination-competitors could reduce the coordinative degree between the ligand and Zr ions to effectively induce defect formation.