AI as your ally: The effects of AI-assisted venting on negative affect and perceived social support.

In recent years, artificial intelligence (AI) chatbots have made significant strides in generating human-like conversations. With AI's expanding capabilities in mimicking human interactions, its affordability and accessibility underscore the potential of AI chatbots to facilitate negative emotional disclosure or venting. The study's primary objective is to highlight the potential benefits of AI-assisted venting by comparing its effectiveness to venting through a traditional journaling platform in reducing negative affect and increasing perceived social support.

Negative work-to-family spillover stress and heightened cardiovascular risk biomarkers in midlife and older adults.

Objectives: The current study aimed to investigate the health implications of negative work-to-family spillover on cardiovascular risk biomarkers.

Methods: In a large-scale cross-sectional dataset of working or self-employed midlife and older adults in the United States (N = 1179), we examined five biomarkers linked to cardiovascular risk, including high-density lipoprotein (HDL) cholesterol, low-density lipoprotein cholesterol, triglyceride, interleukin-6, and C-reactive protein. Negative work-to-family spillover, measured using a four-item self-reported questionnaire, was included into our model to study its association with these cardiovascular risk biomarkers.

Lysine Acetylation, Cancer Hallmarks and Emerging Onco-Therapeutic Opportunities.

Acetylation, a reversible epigenetic process, is implicated in many critical cellular regulatory systems including transcriptional regulation, protein structure, activity, stability, and localization. Lysine acetylation is the most prevalent and intensively investigated among the diverse acetylation forms. Owing to the intrinsic connections of acetylation with cell metabolism, acetylation has been associated with metabolic disorders including cancers.

Expression profiling based on graph-clustering approach to determine colon cancer pathway.

Context: Colorectal cancer is the second leading cause of cancer deaths worldwide. DNA microarray-based technologies allow simultaneous analysis of expression of thousands of genes.

Aim: To search for important molecular markers and pathways that hold great promise for further treatment of patients with colorectal cancer.

Risk factors for oesophageal cancer in Linzhou, China: a case-control study.

Linzhou City has one of the highest incidences of oesophageal cancer in China, and in the world. A case-control study was here conducted to investigate potential risk factors in this area. Linzhou Cancer Registry was used to identify cases of oesophageal cancer, aged between 30 and 75, diagnosed between January 1998 and April 1999.