Screening for HBV, HCV, TP and HIV in pregnant women from various ethnic groups in Yili, Xinjiang, China.

Analyze the infection status of four blood-borne infectious diseases, namely hepatitis B, hepatitis C, syphilis, and acquired immune deficiency syndrome (AIDS), among pregnant women from different ethnic groups in Yili, Xinjiang. The objective is to assess the prevalence of four infectious diseases among pregnant women in this region and provide reference for the prevention and elimination of mother-to-child transmission. Pregnant women of Han and Uygur ethnicity who underwent prenatal screening at our outpatient clinic between 2016 and 2022 were selected for screening for hepatitis B virus surface antigen (HBsAg), antibody to hepatitis C virus (anti-HCV), antibody to treponema pallidum (anti-TP) and antibody to human immunodeficiency virus (anti-HIV) using an enzyme-linked immunosorbent assay (ELISA).

Experimental study on the freezing process of water droplets for ice air jet technology.

Ice air jet technology is one non-destructive, residue-free and environmentally friendly machining process. It is an efficient method to form ice particles by atomizing water droplets in ultra-low temperature environment. The freezing characteristics of water droplets in cryogenic gas and liquid nitrogen environment are visually analyzed, and the effects of droplet volume, ambient temperature are also studied.

Polydatin Inhibits Hepatocellular Carcinoma Cell Proliferation and Sensitizes Doxorubicin and Cisplatin through Targeting Cell Mitotic Machinery.

Polydatin (PD) is a natural compound with anticancer activities, but the underlying mechanisms remain largely unclear. To understand how PD inhibited hepatocellular carcinoma (HCC), we studied PD treatments in HCC HepG2 and SK-HEP1 cells, and normal liver HL-7702 cells. PD selectively blocked the proliferation of HCC cells but showed low toxicity in normal cells, while the effects of doxorubicin (DOX) and cisplatin (DDP) on HCC and normal liver cells were opposite.

OsTKPR2 is part of a sporopollenin-producing metabolon required for exine formation in rice.

The sporopollenin polymer is a major component of the pollen exine. Fatty acid derivatives synthesized in the tapetum are among the precursors of sporopollenin. Progress has been made to understand sporopollenin metabolism in rice; however, the underlying molecular mechanisms remain elusive.

Spillover-feedback effects of social, economic, and environmental footprints based on the "Belt and Road Initiative".

The Belt and Road Initiative (BRI) links China to markets and sources of raw materials around the world while stimulating economic growth in developing countries and leading to widespread and occasionally unexpected social and environmental impacts. Considering that few studies have focused on the trade-embodied social and environmental impacts and two-way impact mechanisms throughout the BRI, this study, for the first time, uses social-economic-environmental footprints and the corresponding indicators of ecological efficiency and environmental stress to methodically measure the spatial distribution and regional transfer among three major regions comprising China (CHN), countries along the Belt and Road countries except China (CBR), and the rest of world (REW) from the standpoint of spillover and feedback effects, to better coordinate sustainable development between environment, economy, and society of the BRI. The results indicated the importance of spillover-feedback effects.

Mechanisms regulating DMTF1β/γ expression and their functional interplay with DMTF1α.

The cyclin D binding myb‑like transcription factor 1 (DMTF1), a haplo‑insufficient tumor suppressor gene, has 3 alternatively spliced mRNA isoforms encoding DMTF1α, β and γ proteins. Previous studies have indicated a tumor suppressive role of DMTF1α and the oncogenic activity of DMTF1β, while the function of DMTF1γ remains largely undetermined. In the present study, the mechanisms regulating DMTF1 isoform expression were investigated and the functional interplay of DMTF1β and γ with DMTF1α was characterized.

Rethinking environmental stress from the perspective of an integrated environmental footprint: Application in the Beijing industry sector.

Individual footprint indicators are limited in that they usually only address one specific environmental aspect. For this reason, assessments involving multiple footprint indicators are preferred. However, the interpretation of a profile of footprint indicators can be difficult as the relative importance of the different footprint results is not readily discerned by decision-makers.

Novel Toll/IL-1 Receptor Homologous Region Adaptors Act as Negative Regulators in Amphioxus TLR Signaling.

Studies have shown that the basal chordate amphioxus possesses an extraordinarily complex TLR system, including 39 TLRs and at least 40 Toll/IL-1R homologous region (TIR) adaptors. Besides homologs to MyD88 and TIR domain-containing adaptor molecule (TICAM), most amphioxus TIR adaptors exhibit domain architectures that are not observed in other species. To reveal how these novel TIR adaptors function in amphioxus Branchiostoma belcheri tsingtauense (bbt), four representatives, bbtTIRA, bbtTIRB, bbtTIRC, and bbtTIRD, were selected for functional analyses.