Use of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Combined With Serum Carcinoembryonic Antigen and Carbohydrate Antigen 19-9 in Predicting Colorectal Cancer Liver Metastasis.

Background: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) combined with serum carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) levels to evaluate the efficacy of colorectal cancer liver metastasis (CRCLM) treatment is still rare.

Purpose: To investigate the predictive value of DCE-MRI combined with serum CEA and CA 19-9 concerning the efficacy of comprehensive treatment for CRCLM.

Materials And Methods: A total of 120 patients with CRC were retrospectively recruited using convenience sampling between May 2019 and March 2024.

A Genome-Wide Characterization of Receptor-like Cytoplasmic Kinase IV Subfamily Members in Identifies the Potential Role of in Plant Osmotic Stress Responses.

The IV subfamily of receptor-like cytoplasmic kinase (RLCK-IV), known as calcium-binding receptor-like cytoplasmic kinases (CRCKs), plays a vital role in plant signal transduction, particularly in coordinating growth and responses to abiotic stresses. However, our comprehension of CRCK genes in , a species characterized as fast-growing and pest-resistant but with drought intolerance, is limited. Here, we identify 6 members of the CRCK subfamily on a genome-wide scale in , denoted as -.

Atmospheric one-pot fractionation and catalytic conversion of lignocellulose in multifunctional deep eutectic solvent system.

This study developed a "one-pot" three-stage process using a "multifunctional" deep eutectic solvent (DES) containing choline chloride (ChCl), ethylene glycol (EG), and protonic acids for the production of phenolic monomers, furfural, and glucose. In the first stage, the DES effectively dissolved over 70 % of lignin and 78 % of hemicellulose while preserving aryl ether bonds in lignin due to the grafting of EG onto the aryl ether bonds. Concurrently, the retention of a near-quantitative amount of cellulose led to a glucose yield of >80 % after enzymatic saccharification.

Selective sweep and GWAS provide insights into adaptive variation of leaves.

Leaf morphology plays a crucial role in predicting the productivity and environmental adaptability of forest trees, making it essential to understand the genetic mechanisms behind leaf variation. In natural populations of , leaf morphology exhibits rich intraspecific variation due to long-term selection. However, there have been no studies that systematically reveal the genetic mechanisms of leaf variation in .

Identification of novel natural anti-browning agents based on phenotypic and metabolites differences in potato cultivars.

This study aimed to elucidate the changes of browning-related metabolite in fresh-cut potato and to identify anti-browning agents. Metabolomics and weighted correlation network analysis (WGCNA) were used to identify metabolites and correlate them with potato browning traits. A total of 79 browning trait-positive-related metabolites and 19 browning trait-negative-related metabolites were obtained from four key modules via WGCNA.

Dynamic Metabolic Responses of Resistant and Susceptible Poplar Clones Induced by Feeding.

Poplar trees are significant for both economic and ecological purposes, and the fall webworm ( Drury) poses a major threat to their plantation in China. The preliminary resistance assessment in the previous research indicated that there were differences in resistance to the insect among these varieties, with '2KEN8' being more resistant and 'Nankang' being more susceptible. The present study analyzed the dynamic changes in the defensive enzymes and metabolic profiles of '2KEN8' and 'Nankang' at 24 hours post-infestation (hpi), 48 hpi, and 96 hpi.

A class-incremental learning approach for learning feature-compatible embeddings.

Humans have the ability to constantly learn new knowledge. However, for artificial intelligence, trying to continuously learn new knowledge usually results in catastrophic forgetting, the existing regularization-based and dynamic structure-based approaches have shown great potential for alleviating. Nevertheless, these approaches have certain limitations.

[Non-small Cell Lung Cancer with Metachronous Mutations of EGFR and ALK Genes: A Case Report and Literature Review].

Multiple primary lung cancer (MPLC) refers to patients with two or more primary lesions of lung cancer. It can be divided into synchronous MPLC (sMPLC) and metachronous MPLC (mMPLC) based on the timing of occurrence. In recent years, the detection rate of MPLC has gradually increased.

Study on the influence of different water and black shale content on the resistivity of loess.

Soil degradation, characterized by the deterioration of soil physical and chemical properties, nutrient loss, and an increase in toxic substances, is a key ecological concern in mining activities. This study explores the use of waste black shale from mining development as an additive to loess to enhance soil properties for reclamation in mining areas. The research includes resistivity and organic carbon content tests on modified reclaimed loess with varying black shale and water contents.

Crystal Composition Transformer: Self-Learning Neural Language Model for Generative and Tinkering Design of Materials.

Self-supervised neural language models have recently achieved unprecedented success from natural language processing to learning the languages of biological sequences and organic molecules. These models have demonstrated superior performance in the generation, structure classification, and functional predictions for proteins and molecules with learned representations. However, most of the masking-based pre-trained language models are not designed for generative design, and their black-box nature makes it difficult to interpret their design logic.

Deformation and Annealing Behavior of Cr Coating Prepared by Pack-Cementation on the Surface of Austenitic Stainless Steel.

In this paper, a Cr coating was prepared by induction heating and pack-cementation chromizing on AISI 304 austenitic stainless steel. Then, the cold-rolling deformation and annealing treatment were introduced to refine the coarse matrix grains caused by pack-chromizing and improve the overall performance of 304 austenitic stainless steel. The phase composition, element distribution, and microstructure of the coating were carefully characterized.

Generative Design of Inorganic Compounds Using Deep Diffusion Language Models.

Due to the vast chemical space, discovering materials with a specific function is challenging. Chemical formulas are obligated to conform to a set of exacting criteria, such as charge neutrality, balanced electronegativity, synthesizability, and mechanical stability. In response to this formidable task, we introduce a deep-learning-based generative model for material composition and structure design by learning and exploiting explicit and implicit chemical knowledge.

Computerized cognitive remediation therapy on cognitive impairment and social function in patients with chronic schizophrenia.

Background: Patients with schizophrenia may have various disease manifestations, most of which gradually tend toward incurable chronic decline, leading to mental disability. The basic symptoms of the disease can impair social function, whereas long-term hospitalization produces hospitalization syndrome, causing serious damage to social function.

Aim: To investigate the effects of Computerized Cognitive Remediation Therapy (CCRT) on cognitive and social functioning in patients with chronic schizophrenia.

Clinical study of dance art therapy on hospitalized patients with chronic schizophrenia.

Background: To explore the effect of dance art on the treatment of hospitalized patients with chronic schizophrenia.

Methods: In a prospective randomized controlled study conducted from June 2019 to June 2020, 120 patients from Shanghai Pudong New Area Mental Health Center were divided into intervention (n = 60) and control (n = 60) groups using a random number table. Control patients received standard drug treatment and nursing care, while the intervention group underwent dance art therapy sessions for 90 minutes twice weekly, in addition to standard care.

PagJAZ5 regulates cambium activity through coordinately modulating cytokinin concentration and signaling in poplar.

Wood is resulted from the radial growth paced by the division and differentiation of vascular cambium cells in woody plants, and phytohormones play important roles in cambium activity. Here, we identified that PagJAZ5, a key negative regulator of jasmonate (JA) signaling, plays important roles in enhancing cambium cell division and differentiation by mediating cytokinin signaling in poplar 84K (Populus alba × Populus glandulosa). PagJAZ5 is preferentially expressed in developing phloem and cambium, weakly in developing xylem cells.

MicroR-1199-5p targeting SRD5A2 promotes the biological behavior and EMT of hypospadias cells.

Hypospadias, an oft-occurring penis anomaly, ranks among neonatal's foremost birth defects. The SRD5A2 can affect male reproductive system development and is abnormally expressed in its epithelial cells. This study exploration aimed at understanding the role of SRD5A2 in the development of hypospadias from a molecular perspective.

Biological fermentation pilot-scale systems and evaluation for commercial viability towards sustainable biohydrogen production.

Featuring high caloric value, clean-burning, and renewability, hydrogen is a fuel believed to be able to change energy structure worldwide. Biohydrogen production technologies effectively utilize waste biomass resources and produce high-purity hydrogen. Improvements have been made in the biohydrogen production process in recent years.

Absorbing oxygen carriers promotes phosphorus recovery from sludge via the microwave thermal conversion process.

This study aims to apply the Absorbing oxygen carriers (AOCs) to induce the migration and transformation of phosphorus compounds during the microwave thermal conversion of sludge so the hard-to-extract organic phosphorus (OP) can be converted to easy-to-extract inorganic phosphorus (IP) and be enriched onto the sludge char. The AOCs were recycled by screen separation from the IP-rich sludge char, with the latter being a renewable phosphorus source from sludge. The AOCs in this novel process enhanced the conversion efficiency of OP into non-apatite inorganic phosphorus (NAlP), which was further converted to apatite inorganic phosphorus (AP).

Effects of cooking methods on the physical properties and in vitro digestibility of starch isolated from Chinese yam.

The objective of this study was to compare the structural and functional attributes of Chinese yam starches obtained via different domestic cooking methods. Cooking changed the crystalline type from the C type to the CB type, and disrupted the short- and long-range molecular order of Chinese yam starch. The average chain length of amylopectin in BOS (boiling starch) was the smallest at 22.

PdRabG3f interfered with gibberellin-mediated internode elongation and xylem developing in poplar.

As a member of the small GTPases family, Rab GTPases play a key role in specifying transport pathways in the intracellular membrane trafficking system and are involved in plant growth and development. By quantitative trait locus (QTL) mapping, PdRabG3f was identified as a candidate gene associated with shoot height in a hybrid offspring of Populus deltoides 'Danhong' × Populus simonii 'Tongliao1'. PdRabG3f localized to the nucleus, endoplasmic reticulum and tonoplast and was primarily expressed in the xylem and cambium.

CFD study of self-cleaning system of multi-stage tangential roller threshing unit for precise buckwheat breeding.

Buckwheat is a globally recognized, nutritionally rich crop with robust adaptability, serving as a multi-purpose plant for its health benefits. Achieving precise and mechanized plot seed harvesting is a critical step in obtaining accurate results in breeding experiments. However, plot breeding requires no seed retention, no mixing, and ensures no accumulation of seed in the threshing unit.