[Experimental and clinical study on the chemosensitivity assay in vitro for head and neck tumor by AgNOR methods].

Objective: To evaluate in vitro chemosensitivity of head and neck tumor to eight kinds of antineoplastic drugs by AgNOR technique.

Method: Fifty-nine cases' fresh specimens were obtained from head and neck tumors. We severed tumor tissue with simple mechanical separation method.

[Reconstruction of anterior skull base defect by pedicle frontal muscle compound flap].

Objective: To evaluate the effect of one stage reconstruction for anterior skull base defect by pedicled frontal muscle compound flap after craniofacial combined approach operation.

Methods: Twelve patients with frontal skull base tumor and fracture (rudimentary cancer 5, malignant melanoma 1, neurogliocytoma 1, ethmoid sinus rhabdomyosarcoma 1, malignant papilloma 1, osteofibroma 2, underwent surgery 1) were included. The compound flap with pedicled frontal muscle galea aponeuroses pericranium was adopted which brought single blood vessel or double, and splinter skull bone.