Publications by authors named "Hsuan-Nu Luk"
Front Psychiatry
November 2021
Article Synopsis
- The study aimed to investigate the effects of escitalopram on sleep EEG power in patients with Major Depressive Disorder (MDD) by comparing sleep and melatonin levels in MDD patients versus healthy controls.
- MDD patients showed significant disruptions in melatonin secretion patterns and sleep architecture, including delayed melatonin peaks and altered brain activity, some of which persisted throughout the 8-week study period.
- After 8 weeks of escitalopram treatment, patients experienced improvements in subjective sleep quality and depressive symptoms, but changes in melatonin rhythm and some sleep parameters remained limited.
