Publications by authors named "Hsuan-Jan Chen"
Biomed Pharmacother
October 2024
Article Synopsis
- * Shikonin (SHK), a compound found in traditional Chinese medicine, shows promise in reducing CBF-AML cell viability by inducing cell cycle arrest, promoting apoptosis, and altering gene expression related to leukemia progression.
- * Animal studies demonstrated that SHK is safe in zebrafish and effectively inhibits leukemia cell growth, especially when combined with cytarabine, highlighting its potential as a new chemotherapy option for CBF-AML.
