Publications by authors named "Hsu Wen-Tung"

Purpose: To evaluate the blood glucose and renal function, determine the prevalence of hyperglycemia/diabetes mellitus (DM) and renal disease (nephropathy), and investigate the association between hyperglycemia/DM and renal disease in patients with viral hepatitis (VH).

Patients And Methods: A total of 491 subjects were included in the study. Patients with VH were further divided into the hepatitis B virus (HBV) infection, hepatitis C virus (HCV) infection, and HBV-HCV co-infection subgroups.

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Article Synopsis
  • The p85α subunit of PI3K influences cancer cell growth and mobility, contributing to their resistance to chemotherapy; TSWU-CD4 is a new compound that reduces cancer cell invasion by lowering MMP-2 expression.
  • TSWU-CD4's impact on MMP-2 and invasion can be reversed by introducing the p85α subunit or specific active forms of MAPK, indicating that p85α and MAPK pathways are crucial for cancer cell motility.
  • The mechanism involves disrupting the interaction between p85α and Rac1 in lipid rafts, suppressing MMP-2 through the PI3K-Akt-ERK-MAP kinase-NF-κB signaling pathway,
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The present study evaluated the effects of physiological serum estrogen during the menstrual cycle on glutathione (GSH) and catalase activities. The sample included 43 healthy females between the ages of 22 and 51 years. The subjects were divided into two groups according to the stage of the menstrual cycle.

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