Care Needs, Challenges, and Experiences of Sexual and Gender Minority Cancer Survivors in Taiwan: Findings from a Qualitative Study.

Objectives: This study aimed to explore the care needs, challenges, and experiences of cancer care among sexual and gender minority (SGM) cancer survivors in Taiwan.

Methods: Semi-structured interviews were conducted face-to-face or telephonically with 30 SGM cancer survivors in Taiwan. Data were analyzed using the socio-ecological model and the constant comparative technique.

Enhancing cultural competence in caring for lesbian, gay, bisexual, and transgender patients: An online training program for Taiwanese student nurses and nurses.

Background: Health disparities exist among lesbian, gay, bisexual, and transgender (LGBT) populations worldwide. However, student nurses and nurse staff have limited knowledge and skills in providing culturally competent nursing care for LGBT patients in Taiwan.

Objectives: This paper describes the development, implementation, and evaluation of an online training program for the cultural competence of student nurses and nurses in Taiwan.

RopB represses the transcription of in the absence of SIP in group A .

RopB is a quorum-sensing regulator that binds to the SpeB-inducing peptide (SIP) under acidic conditions. SIP is known to be degraded by the endopeptidase PepO, whose transcription is repressed by the CovR/CovS two-component regulatory system. Both SIP-bound RopB (RopB-SIP) and SIP-free RopB (apo-RopB) can bind to the promoter; however, only RopB-SIP activates transcription.

[Transgender and Gender Dysphoria: Viewpoints on Clinical Care and Psychological Stress].

Gender identity is a topic of growing interest in mental health research. People with non-conforming gender identity are prone to suffer from stigmatization and bullying, and often present with psychiatric issues. Transgender denotes the broad spectrum of individuals who identify differently from their assigned gender.

Incidence and Effects of Acquisition of the Phage-Encoded Superantigen Gene in Invasive Group A .

The acquisition of the phage-encoded superantigen by scarlet fever-associated group A (, GAS) is found in North Asia. Nonetheless, the impact of acquiring by GAS in invasive infections is unclear. This study initially analyzed the prevalence of + GAS among isolates from sterile tissues and blood.

RocA Regulates Phosphatase Activity of Virulence Sensor CovS of Group A in Growth Phase- and pH-Dependent Manners.

The control of the virulence response regulator and sensor (CovR-CovS) two-component regulatory system in group A (GAS) strains regulates more than 15% of gene expression and has critical roles in invasive GAS infection. The membrane-embedded CovS has kinase and phosphatase activities, and both are required for modulating the phosphorylation level of CovR. Regulator of Cov (RocA) is a positive regulator of and also been shown to be a pseudokinase that interacts with CovS to enhance the phosphorylation level of CovR; however, how RocA modulates the activity of CovS has not been determined conclusively.

Phosphorylation at the D53 but Not the T65 Residue of CovR Determines the Repression of and Transcription in 1- and 49-Type Group A Streptococci.

CovR/CovS is a two-component regulatory system in group A and primarily acts as a transcriptional repressor. The D53 residue of CovR (CovR) is phosphorylated by the sensor kinase CovS, and the phosphorylated CovR protein binds to the intergenic region of to inhibit transcription. Nonetheless, the transcription of and is suppressed in mutants.

Neuregulin/erythroblastic leukemia viral oncogene homolog 3 autocrine loop contributes to invasion and early recurrence of human hepatoma.

Unlabelled: Intrahepatic metastasis is the primary cause of the high recurrence and poor prognosis of human hepatocellular carcinoma (HCC). However, neither its molecular mechanisms nor markers for its prediction before hepatectomy have been identified. We recently revealed up-regulation of erythroblastic leukemia viral oncogene homolog 3 (ERBB3) in human HCC.

Stathmin1 overexpression associated with polyploidy, tumor-cell invasion, early recurrence, and poor prognosis in human hepatoma.

Frequent intrahepatic metastasis causes early tumor recurrence and dismaying prognosis of human hepatocellular carcinoma (HCC). We recently identified overexpression of stathmin1 (STMN1) in human HCC. This study was designed to elucidate the clinical and biological significance of overexpression of STMN1 in HCC.

Identifying apoptosis-evasion proteins/pathways in human hepatoma cells via induction of cellular hormesis by UV irradiation.

Evading apoptosis is pivotal in both of carcinogenesis and resistance to anticancer therapy. We investigated the molecules and pathways of apoptosis evasion in human hepatoma cells by irradiating hepatoma cells with optimized UV (so-called "hormetic responses"). Proteins and pathways related to hormetic responses were identified via proteomic approaches followed by reconstruction of function-networks.

Estradiol Secretion by Tadpole Ovaries Masculinized by Implanted Capsules of Cyanoketone: (cyanoketone/estradiol secretion/Δ -3β-HSD activity/masculinized ovary/Rana tadpole).

Female tadpoles of Rana catesbeiana were laparotomized at metamorphic stages XI-XIII and an empty capsule or one containing cyanoketone (CK), which is an inhibitor of Δ -3β-hydroxysteroid dehydrogenase (Δ -3β-HSD), was implanted intraperitoneally. Ovarian activity of Δ -3β-HSD was examined histochemically 2 months later, estradiol-17β (E ) secretion by the ovaries was measured by RIA 4 months later and histological changes of the ovaries were examined 6 months later. The Δ -3β-HSD activity of the CK-treated ovaries was much lower than that of controls.

The Presence of Intramitochondrial Yolk-crystals in Oocytes of Hypophysectomized Bullfrog Tadpoles*: (intramitochondrial yolk-crystal/tadpole oocyte (Rana)/hypophysectomized tadpole).

Ovaries of hypophysectomized Rana catesbeiana tadpoles. weighing I to 14 g, were prepared for electron microscopic study. The oocytes are at the growth phase, ranging from 50 to 190 μm in diameter.