Evaluation of sub-chronic toxicity of melamine via systematic or oral delivery in adult zebrafish based on behavioral endpoints.

Melamine-tainted products have been found in the market and raised issues about food safety. Recent studies done in rodents and humans demonstrated the toxicities of melamine, especially in causing kidney damage and bladder stone formation. However, very few studies assessed its behavior toxicity in organisms, including fish.

Evaluation of Tacrolimus' Adverse Effects on Zebrafish in Larval and Adult Stages by Using Multiple Physiological and Behavioral Endpoints.

Tacrolimus (FK506) is a common immunosuppressant that is used in organ transplantation. However, despite its importance in medical applications, it is prone to adverse side effects. While some studies have demonstrated its toxicities to humans and various animal models, very few studies have addressed this issue in aquatic organisms, especially zebrafish.

Malignancies after renal transplantation in southern Taiwan: experience in one centre.

Objective: To present data on cancer distribution in renal-transplant recipients in Chinese people, as in Western studies renal-transplant recipients are reportedly at greater risk of malignancies, especially skin cancer, but there is limited information in Chinese people.

Patients And Methods: Using the data of a cancer registry, we compared a hospital-based cohort of 283 renal-transplant recipients between 1981 and 2002 with the general population in Taiwan, to identify the incidence and risk factors of cancer.

Results: The cumulative period of observation was 22 582.

Majocchi's granuloma in a 3-year-old boy.

A 3-year-old boy presented with a 15 x 15-cm papulonodular lesion on his left shin of 8 weeks' duration. The lesion was considered a Majocchi's granuloma caused by Trichophyton tonsurans. He was treated with griseofulvin and topical clotrimazole and hydrocortisone cream and responded well after 8 weeks of treatment.