Publications by Hsin-Tzu Keng

Publications by authors named "Hsin-Tzu Keng"

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The role of revision sinus surgery in the initiation of dupilumab therapy: A real-world study of molecular and cellular features.

Abigail Gaffar Abdul Rahman Alenezi Kathleen M Kelly Heather M Kulaga Hsin-Tzu Keng

Int Forum Allergy Rhinol

October 2024

A persistent type 2 endotype signature exists in recalcitrant chronic rhinosinusitis with nasal polyps mucosa on dupilumab. Revision sinus surgery immediately prior to dupilumab reduces long-term interleukin (IL)-4/IL-13 tissue mRNA. Pre-dupilumab revision surgery is associated with reduced tissue eosinophils and GATA-3+ cells.

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