Publications by authors named "Hsin-Ping Chen"
Article Synopsis
- Drug abuse poses significant health risks and societal issues, with cases reaching 296 million in 2021, prompting the need for more efficient analysis methods.
- A new immuno-MALDI-MS chip was created to enhance the detection of ketamine in urine samples, using antibody-conjugated gold nanoparticles for selective enrichment.
- This method achieves high-throughput screening and accurate quantification of ketamine with a detection limit of 3.3 ng/mL, significantly improving the speed and efficiency of drug abuse analysis compared to traditional methods.
An antibody conjugated boronic acid modified silver chip (ABAS ship) is fabricated as a simple, rapid, accurate, sensitive and cost-effective sample preparation method for abused drug quantification in human urine. Ketamine, one common abused drug, was applied as proof of concept for ABAS chip with high resolution matrix-assisted laser desorption ionization time-of-flight mass spectrometer (MALDI-TOF MS) analysis. The overall testing process required 10 min at part per billion (ppb) sensitivity level, where current drug testing method necessitated several hours with similar sensitivity.
View Article and Find Full Text PDFBackground: Gestational weight gain and weight retention at 1 year after delivery are associated with long-term obesity. We aimed to investigate the effect of laser acupuncture therapy on postpartum weight control.
Methods: We randomly assigned 66 subjects with postpartum weight retention to a laser acupuncture group and control group.
By adding nanotwins to Cu, the surface electromigration (EM) slows down. The atomic mobility of the surface step-edges is retarded by the triple points where a twin meets a free surface to form a zigzag-type surface. We observed that EM can alter the zigzag surface structure to optimize the reduction of EM, according to Le Chatelier's principle.
View Article and Find Full Text PDFObjective: Combinations of Chinese herbal products (CHPs) are widely used for ischemic heart disease (IHD) in Taiwan. We analyzed the usage and frequency of CHPs prescribed for patients with IHD.
Methods: A nationwide population-based cross-sectional study was conducted, 53531 patients from a random sample of one million in the National Health Insurance Research Database (NHIRD) from 2000 to 2010 were enrolled.