Publications by authors named "Hsiao-Yu Yang"

Background: Intrauterine adhesions (IUA) are a challenging clinical problem in reproductive infertility. The most common causes are intrauterine surgery and abortions. We aimed to investigate whether early second-look office hysteroscopy can prevent IUA.

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Background: Previous research has indicated a negative correlation between exclusive breastfeeding and the incidence of Kawasaki disease (KD). However, the validation of this discovery through meta-analytical studies has been lacking. Furthermore, uncertainties persist regarding whether breastfeeding reduces the risk of coronary artery lesions (CAL) or resistance to intravenous immunoglobulin (IVIG).

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Endometriosis is a complex gynecological disease that affects more than 10% of women in their reproductive years. While surgery can provide temporary relief from women's pain, symptoms often return in as many as 75% of cases within two years. Previous literature has contributed to theories about the development of endometriosis; however, the exact pathogenesis and etiology remain elusive.

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Objectives: We aimed to evaluate the association between long working hours, night work, and estimated glomerular filtration rate (eGFR) among young healthcare workers.

Methods: We conducted a retrospective cohort study among healthcare workers in a tertiary medical center in Taiwan from 2002 to 2021. Other than physicians, all hospital employees aged 20-65 years with documented yearly working hours and an annual blood test including creatinine were eligible.

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Article Synopsis
  • The study examined miscarriage rates in patients with poor ovarian response categorized by the POSEIDON criteria, identifying four distinct subgroups with varying success rates in assisted reproductive technology.
  • A total of 1222 clinical pregnancies from POSEIDON patients revealed miscarriage rates ranging from 11.7% to 37.5% across the different subgroups, with advanced maternal age identified as a key risk factor for miscarriage.
  • Although diminished ovarian reserve (DOR) was associated with increased miscarriage risks, it did not significantly impact the outcomes in POSEIDON patients, suggesting age is a more critical concern.
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Background: It is pertinent to understand the perceptions of healthcare workers (HCWs) with their associated personal protective equipment (PPE) usage and heat strain symptoms experienced to effectively combat the negative effects of heat stress during treatment and care activities.

Methods: We evaluated the associated heat stress perceived by HCWs across Asia and validated a questionnaire on perceptions of heat stress, associated PPE usage, and heat strain symptoms experienced. The questionnaire was administered to 3,082 HCWs in six Asian regions.

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Background: Nephrite is an asbestos mineral composed of tremolite and actinolite. Fengtian is a community where nephrite was mined between 1970 and 1980 and asbestos was mined between 1960 and 1985. The lung cancer risk to the surrounding community is unknown.

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Article Synopsis
  • Breath testing with an electronic nose shows potential for detecting lung cancer early, but issues of imbalanced data are often overlooked in studies.
  • This study analyzed breath metabolites from lung cancer patients and healthy individuals using five machine learning algorithms and a special technique to handle imbalanced data, aiming to find the most accurate predictive model.
  • Results indicate that electronic nose screening is very accurate, particularly using the support vector machine algorithm, with high sensitivity and specificity in distinguishing lung cancer from healthy subjects.
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Introduction: Chronic kidney disease (CKD) in agricultural communities is a significant public health issue. We aimed to investigate the epidemiology of CKD among Taiwanese farmers and its association with outdoor heat exposure.

Methods: A nested case-control study was conducted on participants in the National Adult Health Examination (NAHE) from 2012 to 2018.

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Heat stress-related kidney injury has drawn public health attention. This study explored the temporal relationships between impaired kidney function and preceding outdoor heat exposure Taiwan. Data of participants collected through a health screening program was used to assess the association between chronic kidney disease (CKD) and average ambient temperature with various time lag structures.

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Purpose: The relationship among long working hours, night shift working hours, and diabetes is still unclear. We aimed to evaluate the association of long working hours and night shift working hours with diabetes among health care workers.

Methods: We conducted a retrospective cohort study among health care workers in a tertiary medical center in Taiwan from 2002 to 2019.

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Epidemiological studies have reported the association between extreme temperatures and adverse reproductive effects. However, the susceptible period of exposure during pregnancy remains unclear. This study aimed to assess the impact of extreme temperature on the stillbirth rate.

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Background: Previous studies have shown that loss of progesterone receptor (PR) in endometrial cancer (EC) is associated with poor outcomes. Evaluating lymph node metastasis (LNM) is essential, especially before surgical staging. The aim of this study was to investigate the role of PR expression and other clinicopathological parameters in LNM and to develop a prediction model.

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Article Synopsis
  • A study was conducted to explore the link between aristolochic acid (AA) in Chinese herbal products and cancer risk in diabetic patients, as previous research had not addressed this correlation.
  • Using data from Taiwan's National Health Insurance Research Database, researchers tracked diabetes patients over several years to analyze cancer incidences and patterns related to AA exposure.
  • The findings indicated a significant increase in cancer risk - including for kidney, bladder, liver, and prostate cancers - among those exposed to AA, with women also facing heightened risks for extrahepatic bile duct cancer at higher doses.
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(1) Background: Cooking and burning incense are important sources of indoor air pollutants. No studies have provided biological evidence of air pollutants in the lungs to support this association. Analysis of pleural fluid may be used to measure the internal exposure dose of air pollutants in the lung.

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(1) Background: An electronic nose applies a sensor array to detect volatile biomarkers in exhaled breath to diagnose diseases. The overall diagnostic accuracy remains unknown. The objective of this review was to provide an estimate of the diagnostic accuracy of sensor-based breath tests for the diagnosis of diseases.

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For malignant pleural effusions, pleural fluid cytology is a diagnostic method, but sensitivity is low. The pleural fluid contains metabolites directly released from cancer cells. The objective of this study was to diagnose lung cancer with malignant pleural effusion using the volatilomic profiling method.

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Objectives: Chronic kidney disease of undetermined or non-traditional aetiology (CKDu or CKDnT) has been reported in Mesoamerica among farmers under heat stress. Epidemiological evidence was lacking in Asian countries with similar climatic conditions. The objective of this study was to investigate the prevalence of CKDu and possible risk factors.

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Objectives: The objective of this study was to explore the impact of Taiwan's Family Practice Integrated Care Project (FPICP) on hospitalisation.

Design: A population-based cohort study compared the hospitalisation rates for ambulatory care sensitive conditions (ACSCs) among FPICP participating and non-participating patients during 2011-2015.

Setting: The study accessed the FPICP reimbursement database of Taiwan's National Health Insurance (NHI) administration containing all NHI administration-selected patients for FPICP enrolment.

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