Publications by authors named "Hsiang-Ling Lai"
Comparison of escitalopram and paroxetine in the treatment of major depressive disorder.
Int Clin Psychopharmacol
November 2013
Article Synopsis
- This study compared the effectiveness and tolerability of the antidepressants escitalopram and paroxetine in treating major depressive disorder among 399 patients.
- Results showed that escitalopram led to significantly greater reductions in depression symptoms at weeks 6 and 8 compared to paroxetine, although both medications had similar remission rates.
- Escitalopram also caused fewer mild side effects, such as nausea and drowsiness, highlighting its potential advantage, but the study suggests further research with a placebo and double-blind design is needed for more conclusive findings.
Due to their similarity to type IV pilus (Tfp) subunits, the pseudopilins, XpsG, -H, -I, -J and -K, have been predicted to form a pilus-like structure in the type II secretion (T2S) pathway. While overexpression of GspG can result in the formation of bundle structures, the functions of other pseudopilin are not known yet. In this study, we investigate the mutual interaction among the pseudopilins and characterize the specialized minor pseudopilin, XpsJ.
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