Electric Field-Enhanced SERS Detection Using MoS-Coated Patterned Si Substrate with Micro-Pyramid Pits.

This study utilized semiconductor processing techniques to fabricate patterned silicon (Si) substrates with arrays of inverted pyramid-shaped micro-pits by etching. Molybdenum trioxide (MoO) was then deposited on these patterned Si substrates using a thermal evaporation system, followed by two-stage sulfurization in a high-temperature furnace to grow MoS thin films consisting of only a few atomic layers. During the dropwise titration of Rhodamine 6G (R6G) solution, a longitudinal electric field was applied using a Keithley 2400 (Cleveland, OH, USA) source meter.

Survival Outcomes of Patients with Esophageal Cancer Who Did Not Proceed to Surgery after Neoadjuvant Treatment.

Background: This retrospective study examined outcomes in esophageal squamous cell carcinoma (ESCC) patients who did not undergo surgical resection after neoadjuvant chemoradiotherapy (nCRT).

Methods: Patients receiving nCRT between 2012 and 2020 were divided into two groups: group 1 (scheduled surgery) and group 2 (no surgery). Group 2 was further categorized into subgroups based on reasons for not proceeding to surgery: group 2a (disease progression), group 2b (poor general conditions), and group 2c (patient refusal).

Multi-photon properties of branched chromophores derived from indenoquinoxaline and oxadiazole heterocyclic units.

Two chromophoric congeners derived from indenoquinoxaline and oxadiazole are designed, synthesized and characterized for their multi-photon properties in the femtosecond time domain. These two model structures are experimentally found to exhibit strong and widely distributed two- and three-photon activities within the spectral range of 680-1500 nm and the larger congener manifests maximum two- and three-photon absorption cross-section values of 2120 GM (at 750 nm) and ∼85 × 10 cm s (at 1280 nm), respectively. Both two- and three-photon absorption-based optical power-limiting performance of a representative model compound are also evaluated and demonstrated.

The prediction of the dissolution rate constant by mixing rules: the study of acetaminophen batches.

The purpose of this article is to promote two simple and scalable methods to accelerate the formulation development of formulated granules using acetaminophen as a model system. In method I, formulated granules made from the batch of small particle-sized acetaminophen (1) by ball milling the batch of large particle-sized acetaminophen (2), and the mixture of the two batches at equal weights (mix) gave the dissolution rate constants (k) of k(1) = 0.43 +/- 0.