Publications by authors named "Hruza G"

Article Synopsis
  • The study analyzes the use of large language models (LLMs) as educational tools for patients considering Mohs micrographic surgery (MMS), focusing on their effectiveness and accuracy.* -
  • A panel of 15 MMS surgeons assessed LLM-generated responses to common patient questions, finding that most responses were appropriate and 75% rated as mostly accurate, with ChatGPT scoring the highest in accuracy.* -
  • While LLM responses were deemed appropriate, only 33% were considered sufficient for clinical use, and their complexity may hinder patient understanding, highlighting the need for dermatologists to recognize these limitations.*
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The practice of medicine is governed by legislation and regulation at the state and national level. It is crucial, therefore, that dermatologists become and remain involved in the process to advocate for their patients, their practices, and the specialty itself. Maintaining a relationship with one's state and federal senators and representatives is critical for physicians to have a voice in the shaping of health care policy.

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Article Synopsis
  • * Data from 101 cases across 13 countries showed that skin lesions were often the first symptoms of infection, evolving from papules and vesicles to pustules and crusts/scabs as the infection progressed.
  • * The research indicates notable differences from past outbreaks, including early skin lesions and a risk of scarring, while acknowledging potential biases in the registry data.
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Mohs micrographic surgery (MMS) is widely accepted as the gold standard for skin cancer cure, and properly trained surgeons who carry out this procedure are experts in the science and management of skin cancer. There are many potential pitfalls and challenges that a surgeon may encounter while carrying out MMS, and these can increase the likelihood of tumor recurrence and increased patient morbidity. With precise surgical technique, careful tissue handling, and laboratory processes that safeguard against errors, this procedure can provide excellent cure rates for most skin cancers, including melanoma, while maximizing tissue conservation in a low-cost outpatient clinical setting.

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The World Health Organization declared the global monkeypox outbreak a public health emergency of international concern in July 2022. In response, the American Academy of Dermatology and International League of Dermatological Societies expanded the existing COVID-19 Dermatology Registry to become the "AAD/ILDS Dermatology COVID-19, Monkeypox, and Emerging Infections Registry." The goal of the registry is to rapidly collate cases of monkeypox and other emerging infections and enable prompt dissemination of findings to front-line healthcare workers and other members of the medical community.

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Article Synopsis
  • Laser-assisted drug delivery (LADD) is a technique used for medical and cosmetic purposes, but there's a need for better guidelines to help clinicians use it safely and effectively.
  • A comprehensive review of existing studies identified 54 relevant publications that informed new recommendations, which were developed through consensus among a panel of experts.
  • Key findings include that LADD is generally safe for use on various skin types, effective for treating certain skin conditions, and that drug delivery can be optimized through specific techniques, although prophylactic antibiotics are only necessary in certain cases.
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The impact of the COVID-19 pandemic on dermatology practice cannot be overstated. At its peak, the pandemic resulted in the temporary closure of ambulatory sites as resources were reallocated towards pandemic response efforts. Many outpatient clinics have since reopened and are beginning to experience a semblance of pre-pandemic routine, albeit with restrictions in place.

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During the COVID-19 pandemic, rapid, real-world evidence is essential for the development of knowledge and subsequent public health response. In dermatology, provider-facing and patient-facing registries focused on COVID-19 have been important sources of research and new information aimed at guiding optimal patient care. The 7 dermatology registries included in this update now include more than 8000 case reports sourced from physicians and patients from countries all over the world.

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High-quality dermatology patient registries often require considerable time to develop and produce meaningful data. Development time is influenced by registry complexity and regulatory hurdles that vary significantly nationally and institutionally. The rapid emergence of the coronavirus disease 2019 (COVID-19) global pandemic has challenged health services in an unprecedented manner.

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Article Synopsis
  • The study examined skin reactions following COVID-19 vaccinations by reviewing reports from an international registry, focusing on those with available skin biopsy data.
  • Out of 803 reported reactions, 58 cases had sufficient biopsy information, with spongiotic dermatitis being the most frequent histopathologic finding and led to the proposal of the acronym "V-REPP" for these reactions.
  • The research identified 12 additional clinical patterns of skin reactions related to the vaccine, although it noted limitations in the data, indicating that not all cases could be analyzed for incidence rates.
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Background: Cutaneous reactions after messenger RNA (mRNA)-based COVID-19 vaccines have been reported but are not well characterized.

Objective: To evaluate the morphology and timing of cutaneous reactions after mRNA COVID-19 vaccines.

Methods: A provider-facing registry-based study collected cases of cutaneous manifestations after COVID-19 vaccination.

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The American Academy of Dermatology launched DataDerm in 2016 as the clinical data registry platform of the American Academy of Dermatology. DataDerm is approved by the Centers for Medicare & Medicaid Services as a Qualified Clinical Data Registry for the Merit-Based Incentive Payment System. The ultimate purpose of DataDerm is to provide dermatologists with a registry and database that will serve as a vehicle to advance the specialty in the domains of science, discovery, education, quality assessment, quality improvement, advocacy, and practice management.

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