Publications by authors named "Hristo Botev Houbaviy"
Article Synopsis
- The miR-290-295 cluster in mice and its human equivalent, miR-371-373, are mainly active in early embryonic development and germ cells, with some similarities in their seed sequences.
- Sequence analysis indicates that while the mouse cluster has seven pre-miRNAs, the human cluster only has three, yet most of the fundamental seed sequences are preserved between them.
- The study suggests an evolutionary model for these miRNA families based on their shared seed repertoires, which is crucial for understanding their interactions with target genes.
