Publications by authors named "Hrishikesh P Kale"

Article Synopsis
  • Response rates for systemic therapies in cutaneous T-cell lymphoma (CTCL) are low, around 30%, indicating a need for better treatment options; this study focuses on extracorporeal photopheresis (ECP) as a potential solution.
  • A chart review of 52 adults with CTCL treated with ECP from 2017 to 2019 showed that nearly 37% of patients experienced significant improvement, with a median time to response of 6.5 months.
  • The study findings suggest that despite the older age and more advanced disease stages of the patients, ECP remains an effective treatment option for those with CTCL, comparable to results from past clinical trials.
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Objectives: To determine 1-year and 5-year total healthcare costs and healthcare resource (HRU) associated with renal cell carcinoma (RCC) in older Americans, from a healthcare sector perspective.

Materials And Methods: This was a longitudinal, retrospective cohort study using the Surveillance, Epidemiology and End Results-Medicare linked data (2006-2014), which included older (≥66 years) patients with primary RCC and 1:5 matched noncancer controls. Patients/controls were followed from diagnosis (pseudo-diagnosis for controls) until death or up to loss-to-follow-up (censored).

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Introduction: Insomnia diagnosis has been associated with a significant clinical and economic burden on patients and healthcare systems. This study examined changes in healthcare resource use (HCRU) and costs in insomnia patients before and after initiation of suvorexant treatment.

Methods: This retrospective cohort study analyzed Optum Clinformatics Data Mart claims data (Jan 2010-Dec 2018).

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Background: Glioblastoma (GBM) is associated with poor prognosis, large morbidity burden, and limited treatment options. This analysis evaluated real-world treatment patterns, overall survival, resource use, and costs among Medicare patients with GBM.

Methods: This retrospective observational study evaluated Medicare patients age 66 years or older with newly diagnosed GBM using the Surveillance, Epidemiology, and End Results (SEER)-Medicare linked data from 2007 through 2013.

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Objective: This study examined the economic burden of renal cell carcinoma (RCC) among older adults. The study also examined healthcare costs by types of resources used and stage at which RCC was diagnosed.

Methods: The study analyzed the Surveillance Epidemiology and End Result-Medicare linked data.

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Background: Nonadherence to specialty drugs has been associated with poor clinical and economic outcomes. Studies conducted using commercial health plans suggest that patients who use specialty pharmacies have higher adherence compared with patients using retail pharmacies. However, little is known about the frequency of dispensing channel use or the association of dispensing channel use with adherence to specialty drugs among Medicare Part D beneficiaries.

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Background: Cancer-related financial burden has been linked to cancer survivors (CS) forgoing/delaying medical care, skipping follow-up visits, and discontinuing medications. To the authors' knowledge, little is known regarding the effect of financial burden on the health-related quality of life of CS.

Methods: The authors analyzed 2011 Medical Expenditure Panel Survey data.

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