Publications by authors named "Howard Hz Thom"
Background: Atrial fibrillation (AF) is a common cardiac arrhythmia that increases the risk of thromboembolic events. Anticoagulation therapy to prevent AF-related stroke has been shown to be cost-effective. A national screening programme for AF may prevent AF-related events, but would involve a substantial investment of NHS resources.
View Article and Find Full Text PDFOral anticoagulants for primary prevention, treatment and secondary prevention of venous thromboembolic disease, and for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis and cost-effectiveness analysis.
Jonathan Ac Sterne Pritesh N Bodalia Peter A Bryden Philippa A Davies Jose A López-López Howard Hz Thom
Health Technol Assess
March 2017
Article Synopsis
- - Warfarin is commonly used for stroke prevention in atrial fibrillation (AF) and for treating venous thromboembolism (VTE), but its use is often limited due to the risk of bleeding and the costs associated with monitoring therapy.
- - The study aimed to identify the most effective oral anticoagulants for stroke prevention in AF as well as for the prevention and treatment of VTE through systematic reviews and cost-effectiveness analyses.
- - The research focused on comparing novel oral anticoagulants (NOACs), warfarin, and low-molecular-weight heparin (LMWH), evaluating outcomes such as stroke incidence, VTE occurrence, bleeding complications, and overall cost-effectiveness.