Prematurity, chorioamnionitis, and the development of recurrent wheezing: a prospective birth cohort study.

Background: Prematurity (< 37 weeks) has been inconsistently associated with asthma and wheezing. Chorioamnionitis may promote both prematurity and inflammatory pathways in infants' airways.

Objective: To investigate the relationship of prematurity and chorioamnionitis with the development of early childhood recurrent wheezing.