Publications by authors named "Houyuan Chen"
Article Synopsis
- The study evaluated the effectiveness and safety of combining tislelizumab with low-dose nab-paclitaxel in treating muscle-invasive bladder cancer (MIBC) patients.
- In a phase 2 trial involving 62 participants, 52% achieved a clinical complete response, indicating a positive treatment outcome.
- The treatment was generally well tolerated, with only 9.7% of patients experiencing severe side effects, making it a promising preoperative option for MIBC.
Construction and Validation of a Prognostic Model Based on Pyroptosis-related Genes in Bladder Cancer.
Comb Chem High Throughput Screen
September 2024
Background: Bladder cancer (BCa) is a highly prevalent disease with a poor prognosis. There is no better forecasting method for it yet. Current studies demonstrate that pyroptosis is involved in the development and progression of various cancers.
View Article and Find Full Text PDFA temperature measurement subsystem (TMS) is a critical piece of infrastructure of the space gravitational wave detection platform, necessary for monitoring minuscule temperature changes at the level of 1μK/Hz1/2 within the electrode house, in the frequency range of 0.1mHz to 1Hz. The voltage reference (VR), a key component of the TMS, must possess low noise characteristics in the detection band to minimize the impact on temperature measurements.
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- TRPV (Transient Receptor Potential Cation Channel Subfamily V) is implicated in cancer initiation and treatment, but its role across various cancers (pan-cancer) is under-researched.
- The study utilized several databases to analyze TRPV gene expression differences, mutation data, and their impact on cancer prognosis and treatment effectiveness, particularly in bladder cancer and other types.
- Results indicated that TRPV2 expression is notably lower in many cancer types, and further analyses explored its potential as a predictive marker for treatment responses and overall survival outcomes.
Studying high-sensitivity fiber-optic temperature sensors is vital in pursuing high-precision temperature measurement. We propose a liquid-sealed multimode interference fiber temperature sensor with a double-taper structure. The influence of structure and sealed-liquid material on the temperature sensitivity of the sensor is analyzed experimentally.
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