Publications by authors named "Houwen Ding"
Urinary acetone in urine is produced from fat metabolism in human body, which can be accelerated in diabetic patients because of insufficient utilization and storage of glucose. In this study, we tried to develop a novel diagnosis method of type 2 diabetes (T2D) through sniffing urinary acetone by a proton transfer reaction mass spectrometry (PTR-MS). A total of 180 T2D patients and 180 healthy volunteers were recruited from three hospitals for multicenter study.
View Article and Find Full Text PDFAnalysis of volatile organic compounds from deep airway in the lung through intubation sampling.
Anal Bioanal Chem
November 2022
Article Synopsis
- Exhaled volatile organic compounds (VOCs) can indicate disease but are often contaminated by food and bacteria from the mouth and nasal passages.
- This study collected and analyzed deep airway exhalation using intubation to better identify true body metabolic VOCs, employing methods like proton transfer reaction mass spectrometry (PTR-MS).
- Results showed that certain VOCs (ethanol, methyl mercaptan, phenol) found in oral exhalation were at lower levels in deep airway samples, suggesting they likely originate from food and bacteria rather than metabolism, guiding future clinical research on VOCs.