Exploring the antioxidant, antidiabetic, and antibacterial potential of postbiotic compounds derived from O7S1.

Probiotic bacteria are distinguished by their ability to produce various functional postbiotic metabolites. Therefore, this study aimed to explore the antioxidant, antidiabetic, and antibacterial properties of two postbiotics generated by O7S1 ( O7S1) during the fermentation process: cell-free supernatant (CFS) and exopolysaccharides (EPS). The antioxidant potential of these postbiotics was assessed using various radical scavenging assays and ferric-reducing antioxidant potential.

A comparative study on biodegradation of low density polyethylene bags by a Rhizopus arrhizus SLNEA1 strain in batch and continuous cultures.

Biodegradation poses a challenge for environmentalists and scientific community, offering a potential solution to the plastic waste problem. This study aims to investigate the biological degradation of low-density polyethylene (LDPE) bags by a fungus in both batch and continuous cultures, with the goal of identifying an eco-friendly and cost-effective waste management strategy. The fungal strain Rhizopus arrhizus SLNEA1, isolated from a landfill located in northeastern Algeria, was tested for its capability to degrade LDPE films and utilize them as a sole carbon source in batch (α-LDPE) and continuous (γ-LDPE) cultures.

Exploring the hepatoprotective potential of the probiotic Lactiplantibacillus plantarum E1K2R2 and its exopolysaccharide-postbiotic on ibuprofen-induced acute liver injury in rats.

The present study investigates the hepatoprotective effect of a probiotic Lactiplantibacillus plantarum E1K2R2 and its exopolysaccharide (EPS) against ibuprofen-induced acute liver injury, and to explore the involved underlying mechanisms. Hepatotoxicity was induced by administration of a single dose of ibuprofen (200 mg/kg body weight). The Lpb.

Prophylactic Effect and Antiulcerogenic Potential of Probiotic Lactiplantibacillus plantarum E1K2R2 and its Exopolysaccharide Against Ibuprofen-Induced Acute Gastric Ulcer.

Lactiplantibacillus plantarum (Lpb. plantarum), as a safe probiotic microorganism, has been documented for its production of multiple bioactive compounds, such as exopolysaccharides (EPS), which have been used in the treatment of many gastrointestinal diseases, including gastric ulcers. The present study aims to investigate the prophylactic and antiulcerogenic effects of the potential probiotic Lbp.

Removal of diclofenac by a local bacterial consortium: UHPLC-ESI-MS/MS analysis of metabolites and ecotoxicity assessment.

Diclofenac (DCF) belongs to the class of nonsteroidal anti-inflammatory drugs, which is one of the most consumed by population and detected in raw sewage. Several studies have reported variable removal rates by biodegradation of diclofenac in wastewater treatment plants (WWTPs). This study deals with the evaluation of the biodegradation of DCF by a bacterial consortium (obtained from pure cultures of Enterobacter hormaechei D15 and Enterobacter cloacea D16), which were isolated from household compost and Algerian WWTP, respectively, as sole carbon source and by co-metabolism, using glucose as carbon source.

Assessment of Streptococcus thermophiles Antioxidant Efficiency and its Role in Reducing Paracetamol Hepatotoxicity.

Background: Probiotics have attracted a great attention aiming to develop natural non-toxic antioxidants, because of their role in decreasing the risk of reactive oxygen species [ROS] accumulation.

Objectives: The purpose of this study was to assess the antioxidant activity of a probiotic ssp [St.sa] and to evaluate its protective effect against the oxidative stress induced by a toxic dose of paracetamol in Wistar rats.

Effect of probiotic supplementation on oxidative stress markers in rats with diclofenac-induced hepatotoxicity.

In this study, we have investigated the effect of an antioxidant probiotic pretreatment toward an overdose of diclofenac in rats (100 mg/kg bw). Rats were treated daily with the probiotic Streptococcus salivarius St.sa (10 CFU) during seven successive days and then received a single treatment with diclofenac overdose in distilled water.

Coss and Durieu: Phytochemical Composition and Biological Activities.

is an Algerian-Tunisian endemic species, which has not been studied yet. Ethyl acetate (EA) and -butanol (Bu) fractions obtained from were investigated for their health benefit properties, in particular with respect to in vivo/in vitro anti-inflammatory and antioxidant activities, as well as their potential to inhibit key enzymes with impact in diabetes (α-glucosidase and α-amylase). The fractions had a distinct phytochemical composition, of which EA was richer in total phenolic compounds (225 mg GAE/g) and mostly composed of the phenylethanoid acetyl martynoside.

Biological Removal of the Mixed Pharmaceuticals: Diclofenac, Ibuprofen, and Sulfamethoxazole Using a Bacterial Consortium.

The presence of pharmaceuticals at low concentrations (ng to μg) in the environment has become a hot spot for researchers in the past decades due to the unknown environmental impact and the possible damages they might have to the plantae and fauna present in the aquatic systems, as well as to the other living organisms. The aim of the present investigation was to develop a bacterial consortium isolated from different origins to evaluate the ability of such a consortium to remove a mixture of pharmaceuticals in the batch system at lab scale, as well as assessment of its resistance to the other micropollutants present in the environment. Using a closed bottle test, biodegradation of the mixed pharmaceuticals including Diclofenac (DCF), Ibuprofen (IBU), and Sulfamethoxazole (SMX) (at a concentration of 3 mg.

Metabolic and Co-Metabolic Transformation of Diclofenac by Enterobacter hormaechei D15 Isolated from Activated Sludge.

The presence of non-steroidal anti-inflammatory drugs, such as diclofenac (DCF), in the environment, is an emerging problem due to their harmful effects on non-target organisms, even at low concentrations. We studied the biodegradation of DCF by the strain D15 of Enterobacter hormaechei. The strain was isolated from an activated sludge, and identified as E.

Biodegradation of native feather keratin by Bacillus subtilis recombinant strains.

A mixed culture containing two recombinant Bacillus subtilis strains; was used to hydrolyze 1% chicken feather; both were previously transformed with late-expressed and early expressed alkaline protease (aprE) carrying plasmids pS1 and p5.2, respectively. Proteolytic and keratinolytic activities of the mixed culture increased in parallel with those of the culture of B.

Optimization of bacitracin production by Bacillus licheniformis B5.

Production of the polypeptide antibiotic bacitracin by a newly isolated Bacillus licheniformis B5 strain, using a laboratory medium was optimized. A medium of the following conditions was obtained: 1.5% glycerol as carbon source, 0.