Modulatory Effect of Chaetomorpha gracilis on Erythrocytes Functions and Metabolic Disorders in Mice Fed a High-cholesterol Diet.

The current study was carried out to estimate the protective effect of methanolic extract of Chaetomorpha gracilis (MECG) against High Cholesterol Diet (HCD) induced erythrocyte damage in mice. The results of the in vitro assay showed that MECG have higher antioxidant capacities in the DPPH, TAC, ABTS, NBT, NO inhibition assays. The HPLC analysis confirmed that this potential antioxidant seems to be due to the active compounds, in particular polyphenols, flavonoids.

Antioxidant and hepatopreventive effects of extract against carbon tetrachloride-induced hepatotoxicity in rats.

The present study aimed to investigate the preventive effects of methanol fraction from leaf extract (MECA), associated with its phytochemical content, on CCl-induced hepatic toxicity in adult rats. In the controls, CCl induced an increase of serum biochemical parameters and triggered oxidative stress in the liver. MECA caused significant reductions in CCl-elevated levels of hepatic markers, total cholesterol, triglycerides, and low-density lipoprotein and increased the level of high-density lipoprotein compared to the CCl group.

Protective effect of essential oil of bark on hepatic and renal toxicity induced by carbon tetrachloride in rats.

The inner bark of cinnamon () is widely used as a spice. Cinnamon plants are also a valuable source of essential oil used for medicinal purposes. The present study aimed to investigate the composition and in vitro antioxidant activity of essential oil of bark (CvEO) and its protective effects in vivo on CCl-induced hepatic and renal toxicity in rats.

Evaluation of the hepatoprotective effect of combination between fermented camel milk and leaves extract against CCl induced liver toxicity in mice.

The present study was conducted to evaluate the in vitro antioxidant activity of fermented camel milk with subsp. (FCM-LLC) alone, extract (R) alone and their combination and to investigate their hepatopreventive effects against CCl liver damage in mice. The antioxidant activity in vitro of FMC-LLC supplemented with R exhibited the highest free radical scavenging and ferric reducing power activities.

The preventive effect of aqueous extract of Rosemary () leaves against the nephrotoxicity of carbon tetrachloride in mice.

The present study aimed to evaluate the performance effect of aqueous extract of (AERO) against the kidney toxicity induced by CCl in mice. The results showed that the renal damage induced by CCl was associated with a rise in oxidative stress monitored by a significant increase of TBARS and PCO levels (+89% and +136% respectively,  < .001) and a significant decrease of GSH level (-68%,  < .

Fermented camel milk by Lactococcus lactis subsp. cremoris attenuates erythrocytes oxidative stress-induced hematological and immunological damage in CCl-intoxicated mice.

Fermented camel by Lactococcus lactis subsp. cremoris has been recently discovered to protect against the toxic effect of carbon tetrachloride (CCl), but its beneficial effects in the presence of oxidative stress in the erythrocytes have not been established. In the present study, 28 mice were randomly divided into four groups: control group; CCl group: intoxicated by a single intraperitoneal injection (ip) of CCl; group FCM-LLC + CCl: pretreated with FCM-LLC daily during 14 days, and received a single dose of CCl.

Fermented camel milk prevents carbon tetrachloride induced acute injury in kidney of mice.

Fermented milk is known to possess potent antioxidant activity. The present study was undertaken to assess the preventive effect of fermented camel milk (FCM) prepared using lactococcus lactis subsp. cremoris against CCl4 induced kidney damage in mice.

Cardiopreventive effects of camel milk against carbon tetrachloride induced oxidative stress, biochemical and histological alterations in mice.

The present study was designed to examine the preventive effects of camel milk (CM) against the toxic effects of acute exposure to carbon tetrachloride (CCl) on the heart tissue of mice. Administration of a single dose of CCl caused cardio toxicity as monitored by an increase in lipid peroxidation (thiobarbituric acid reactive substances), protein carbonyl level and antioxidant markers (superoxide dismutase, catalase, glutathione peroxidase, glutathione and vitamin C) in the heart tissue. Moreover, CCl caused a distinguished rise of plasma aspartate aminotransferase, lactate dehydrogenase, troponin I, and creatine kinase activities.

Effects of Spirulina platensis on lipid peroxidation, antioxidant defenses, and tissue damage in kidney of alloxan-induced diabetic rats.

Chronic hyperglycemia in diabetes causes free radicals overproduction, which contributes to the development of diabetic nephropathy. In modern medicine, no satisfactory therapy is available to cure diabetes mellitus. In that context, we investigated the potential therapeutic action of spirulina-enriched diet on renal impairment and oxidative stress in diabetic rats.

Beneficial effects of fermented camel milk by lactococcus lactis subsp cremoris on cardiotoxicity induced by carbon tetrachloride in mice.

Carbon tetrachloride (CCl) is a xenobiotic present in the environment, can cause harmful effects on human health. In the present study, we attempted to elucidate the cardiopreventive potential of the fermented camel milk by lactococcus lactis subsp cremoris (FCM-LLC) against the toxic effects of acute exposure to CCl on heart tissue of mice. Twenty-eight mice's were divided into four groups of seven each: group (C) served as control; group (FCM-LLC) received only 100mgL of FCM-LLC/kg body weight daily for 15days; group (CCl) was administered by a single dose of CCl (10mL/kg in 0.

Immunomodulatory and antioxidant protective effect of Sarcocornia perennis L. (swampfire) in lead intoxicated rat.

Lead (Pb) is a very toxic metal present in the environment, causing disturbances of several functions. Preventive or curative effects of halophytic plants against these disorders may be a promising and safe therapeutic strategy. Thus, this study was designed to evaluate in vivo immunomodulatory and antioxidant effects of Sarcocornia perennis extract (Sp) against lead toxicity in rats.

Evaluation of Tunisian milk quality in dairy herds: Inter-relationship between chemical, physical and hygienic criteria.

The objective of this paper was to evaluate the global milk quality in Tunisian dairy herds. Samples of milk were analyzed for chemical, physical and hygienic parameters. Milk total solids, fat content and density were consistently correlated and one of them can be used as a chemical indicator of milk quality.

Analysis of raw milk quality at reception and during cold storage: combined effects of somatic cell counts and psychrotrophic bacteria on lipolysis.

The objective of the article was to analyze the influence of psychrotrophic bacteria counts (PBCs) and somatic cell counts (SCCs) on the extent of lipolysis in bulk samples of cow's milk at reception and during cold storage. Samples of milk were analyzed on the day of sampling and subsequently during cold storage. The acidity, fat, density, chloride content, electrical conductivity (EC), bulk milk SCCs (BMSCC), and PBC values were analyzed on the day of sampling and the levels of acidity, EC, SCC, and PBC were analyzed during cold storage at 4 °C for 72 h.

Total and differential bulk cow milk somatic cell counts and their relation with antioxidant factors.

In the present study, the relationship between total bulk milk somatic cell counts (BMSCC), differential BMSCC (macrophage, lymphocyte, and polymorphonuclear leukocytes), and antioxidant enzymes was investigated. Forty-three samples of bulk milk were selected randomly from eight dairy farms in the region of Sfax (Tunisia) in winter, from November 2005 to February 2006. Bulk milk samples were analyzed for antioxidant enzymes such as catalase, SOD and GSHPx activity and differential SCC.